6 Result(s)
within
Daeui Park
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessAcetylcholinesterase and monoamine oxidase-B inhibitory activities by ellagic acid derivatives isolated from Castanopsis cuspidata var. sieboldii
Among 276 herbal extracts, a methanol extract of Castanopsis cuspidata var. sieboldii stems was selected as an experimental source for novel acetylcholinesterase (AChE) inhibitors. Five compounds were isolated fr...
-
Article
Open AccessAcetylcholinesterase and butyrylcholinesterase inhibitory activities of khellactone coumarin derivatives isolated from Peucedanum japonicum Thurnberg
Cholinesterase (ChE) and monoamine oxidase (MAO) inhibitors have been attracted as candidate treatments for Alzheimer's disease (AD). Fifteen khellactone-type coumarins from the roots of Peucedanum japonicum Thun...
-
Article
Open AccessContribution of SLC22A12 on hypouricemia and its clinical significance for screening purposes
Differentiating between inherited renal hypouricemia and transient hypouricemic status is challenging. Here, we aimed to describe the genetic background of hypouricemia patients using whole-exome sequencing (W...
-
Article
Open AccessDifferences in the molecular signatures of mucosal-associated invariant T cells and conventional T cells
Mucosal-associated invariant T (MAIT) cells exhibit different characteristics from those of TCRα7.2− conventional T cells. They play important roles in various inflammatory diseases, including rheumatoid arthriti...
-
Article
Open AccessLow-dose irradiation promotes Rad51 expression by down-regulating miR-193b-3p in hepatocytes
Current evidence indicates that there is a relationship between microRNA (miRNA)-mediated gene silencing and low-dose irradiation (LDIR) responses. Here, alterations of miRNA expression in response to LDIR exp...
-
Article
Open AccessA key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction
Knowledge of genes essential for the life-extending effect of dietary restriction (DR) in mammals is incomplete. In this study, we found that neuropeptide Y (Npy), which mediates physiological adaptations to e...
