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Article
Real-world experience of olaparib as maintenance therapy in BRCA-mutated recurrent ovarian cancer
The primary objective of our study was to investigate the effectiveness and safety of olaparib maintenance therapy in patients with BRCA-mutated recurrent ovarian cancer in daily practice. The secondary objec...
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Article
Open AccessTrends in treatment during the last stages of life in end-stage gynecologic cancer patients who received active palliative chemotherapy: a comparative analysis of 10-year data in a single institution
Palliative chemotherapy should be used with caution when attempting to alleviate symptoms in patients with end-stage cancer. However, palliative chemotherapy continues to be utilized in cancer patients during ...
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Article
Open AccessThe efficacy of sentinel lymph node map** with indocyanine green in cervical cancer
Lymph node metastasis is a significant predictive factor for disease recurrence and survival in cervical cancer patients. Given the importance of lymph node metastasis, it is imperative that patients harboring...
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Article
Open AccessLRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycle
Although endometrial cancer is the most common type of gynecological malignancy in developed countries, its molecular etiology is not well understood. Leucine-rich repeat and immunoglobulin-like domain 2 (LRIG...
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Article
Open AccessFeasibility of uterine preservation in the management of early-stage uterine adenosarcomas: a single institute experience
We aimed to evaluate the efficacy and the safety of uterine preservation in patients with early-stage uterine adenosarcoma who want to preserve future fertility.
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Article
Laparoendoscopic single-site versus conventional laparoscopic-assisted vaginal hysterectomy for benign or pre-invasive uterine disease
The aim of this study was to compare the surgical outcomes of laparoendoscopic single-site (LESS) versus conventional laparoscopic-assisted vaginal hysterectomy (LAVH) in patients with benign or pre-invasive u...
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Article
Open AccessIER3 is a crucial mediator of TAp73β-induced apoptosis in cervical cancer and confers etoposide sensitivity
Infection with high-risk human papillomaviruses (HPVs) causes cervical cancer. E6 oncoprotein, an HPV gene product, inactivates the major gatekeeper p53. In contrast, its isoform, TAp73β, has become increasing...
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Article
Prognostic factors and treatment outcomes of patients with uterine sarcoma: analysis of 127 patients at a single institution, 1989–2007
Uterine sarcoma is a rare malignancy with the worst prognosis of all uterine cancers. This study evaluated the prognostic factors and treatment outcomes of patients with this disease.
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Rapid Regulation of Insulin-Like Growth Factor Binding Protein-1 Transcription by Insulin in Vivo and in Vitro
Insulin-like growth factor binding protein-1 (IGFBP-1) is distinctive among the IGFBPs in human plasma in its dynamic regulation by metabolic changes [reviewed in 1]. IGFBP-1 levels are increased by acute fasting...
