14 Result(s)
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Article
Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects
The surge in reports describing non-coding RNAs (ncRNAs) has focused attention on their possible biological roles and effects on development and disease. ncRNAs have been touted as previously uncharacterized r...
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Article
Open AccessTriosephosphate isomerase 1 may be a risk predictor in laryngeal squamous cell carcinoma: a multi-centered study integrating bulk RNA, single-cell RNA, and protein immunohistochemistry
Although great progress has been made in anti-cancer therapy, the prognosis of laryngeal squamous cell carcinoma (LSCC) patients remains unsatisfied. Quantities of studies demonstrate that glycolytic reprogram...
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Open AccessNR4A3 and CCL20 clusters dominate the genetic networks in CD146+ blood cells during acute myocardial infarction in humans
CD146 is a tight junction-associated molecule involved in maintaining endothelial barrier, and balancing immune–inflammation response, in cardiovascular disease. Notably, peripheral CD146+ cells significantly ups...
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Article
Open AccessThe genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma
Epstein-Barr virus (EBV)-associated gastric carcinomas (EBVaGCs) present unique molecular signatures, but the tumorigenesis of EBVaGCs and the role EBV plays during this process remain poorly understood.
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Article
Therapeutic effect of **longshe Granule (金龙蛇颗粒) on quality of life of stage IV gastric cancer patients using EORTC QLQ-C30: A double-blind placebo-controlled clinical trial
To evaluate the impact of **longshe Granule (金龙蛇颗粒, JLSG) on quality of life (QOL) of stage IV gastric cancer patients.
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Article
Differences in the origin of philosophy between Chinese medicine and western medicine: Exploration of the holistic advantages of Chinese medicine
To explore advantages of Chinese medicine (CM) by analyzing differences in the origin of philosophy for human health between CM and Western medicine (WM). Methodologically, a distinctive feature of CM is its s...
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Article
Open AccessOverexpression of FoxM1 is associated with tumor progression in patients with clear cell renal cell carcinoma
Fork head box M1 (FoxM1) is a proliferation-associated transcription factor essential for cell cycle progression. Numerous studies have documented that FoxM1 has multiple functions in tumorigenesis and its ele...
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Article
Tumor interstitial fluid and gastric cancer metastasis: An experimental study to verify the hypothesis of “tumor-phlegm microenvironment”
To extract tumor interstitial fluid (TIF) from MKN-45 gastric cancer which is similar to “muddy phlegm” in Chinese medicine and observe influences of MKN-45 tumor interstitial fluid (MKN-45 TIF) intervention o...
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Article
Open AccessActivated mammalian target of rapamycin is a potential therapeutic target in gastric cancer
The mammalian target of rapamycin (mTOR) plays a key role in cellular growth and homeostasis. The purpose of our present study is to investigate the expression of activated mTOR (p-mTOR) in gastric cancer pati...
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Article
Tumor interstitial fluid and postoperative recurrence of tumors: An experimental study for verifying hypothesis of “tumor-phlegm microenvironment”
To explore a method of extracting tumor interstitial fluid (TIF) which is similar to muddy phlegm in Chinese medicine (CM), interleukin-8 (IL-8) in concentration was taken as the representative of the content ...
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Article
Open AccessRelationship between H.Pylori infection and clinicopathological features and prognosis of gastric cancer
Aimed to assess the relationship between H.Pylori and the clinicopathological features and prognosis of gastric cancer by quantitative detection of H.Pylori.
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Article
MicroRNAs in Cardiac Remodeling and Disease
MicroRNAs (miRNAs) are a large sub-group of small non-coding RNAs, which have been demonstrated to post-transcriptionally regulate the expression of protein-coding genes in a wide-range biological process. miR...
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Article
Open AccessHigher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB
Cancer stem cell model suggested that tumor progression is driven by the overpopulation of cancer stem cells and eradicating or inhibiting the symmetric division of cancer stem cells would become the most impo...
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Article
Effects of red Ginseng on the congestive heart failure and its mechanism
Forty-five patients with class IV cardiac function were divided randomly into three groups, group I (digoxin group), group II (red Ginseng group) and group III (red Ginseng plus digoxin group). Each group cons...
