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Article
Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects
The surge in reports describing non-coding RNAs (ncRNAs) has focused attention on their possible biological roles and effects on development and disease. ncRNAs have been touted as previously uncharacterized r...
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Article
Effect of Artificial Cooling Extrusion on Microstructure and Mechanical Properties of Mg–Zn–Y Alloys
Microstructure and mechanical properties of Mg–Zn–Y alloys with different Zn/Y atomic ratios with or without artificial cooling (AC) extrusion were systematically investigated in this work. The results show th...
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Article
Open AccessAssociations of maternal serum concentration of iron-related indicators with birth outcomes in Chinese: a pilot prospective cohort study
Previous studies of maternal iron and birth outcomes have been limited to single indicators that do not reflect the comprehensive relationship with birth outcomes. We aimed to investigate the relationship betw...
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Article
Fixed-Time Disturbance Observer-Based Control for Uncertainty Systems Applied to Permanent-Magnet Speed Control
For a class of uncertain systems, a fixed-time disturbance observer is suggested. The proposed observer not only estimated the disturbance but also ensured the fixed-time convergence, leading to the increased ...
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Chapter and Conference Paper
Structural Evolution and Reservoir Control Characteristics of Sichuan Basin
In order to clarify the hydrocarbon accumulation characteristics of continental clastic rock in Sichuan Basin, this paper analyzes the control of regional tectonic evolution characteristics on hydrocarbon accu...
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Article
Understanding the spatial interaction of ultrasounds based on three-dimensional dual-frequency ultrasonic field numerical simulation
A transient 3D model was established to investigate the effect of spatial interaction of ultrasounds on the dual-frequency ultrasonic field in magnesium alloy melt. The effects of insertion depth and tip shape...
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Article
Open AccessTriosephosphate isomerase 1 may be a risk predictor in laryngeal squamous cell carcinoma: a multi-centered study integrating bulk RNA, single-cell RNA, and protein immunohistochemistry
Although great progress has been made in anti-cancer therapy, the prognosis of laryngeal squamous cell carcinoma (LSCC) patients remains unsatisfied. Quantities of studies demonstrate that glycolytic reprogram...
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Article
Changes in lake area and water level in response to hydroclimate variations in the source area of the Yellow River: a case study from Lake Ngoring
In the north-eastern Qinghai-Tibet Plateau (QTP), the source area of the Yellow River (SAYR) has been experiencing significant changes in climatic and environmental conditions in recent decades. To date, few s...
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Article
Open AccessA defect in mitochondrial protein translation influences mitonuclear communication in the heart
The regulation of the informational flow from the mitochondria to the nucleus (mitonuclear communication) is not fully characterized in the heart. We have determined that mitochondrial ribosomal protein S5 (MR...
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Article
Open AccessImproving the genome and proteome annotations of the marine model diatom Thalassiosira pseudonana using a proteogenomics strategy
Diatoms are unicellular eukaryotic phytoplankton that account for approximately 20% of global carbon fixation and 40% of marine primary productivity; thus, they are essential for global carbon biogeochemical c...
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Article
Mesenchymal stem cells in fibrotic diseases—the two sides of the same coin
Fibrosis is caused by extensive deposition of extracellular matrix (ECM) components, which play a crucial role in injury repair. Fibrosis attributes to ~45% of all deaths worldwide. The molecular pathology of ...
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Article
Effect of Converter Scrap Ratio on Carbon Emission in BF-LD Process
Increasingly stringent environmental protection policies are putting increasing pressure on the steel industry to limit carbon emissions. Scrap ratio has a large impact on carbon emissions, but there is a lack...
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Article
Effect of Ni–P content on microstructure and mechanical properties of Fe–Ni–P alloy
A series of Fe–Ni–P alloys with different Ni–P contents were prepared by micro-press sintering, and the influence of the contents on the final microstructure and mechanical properties was evaluated. Sample Fe–...
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Article
Preparation and compression behavior of Fe–Ni–P/porous-Fe/Fe–Ni–P composites
Porous-Fe–N alloys designed for light weight or energy absorption are inevitably facing the compromise of deteriorated mechanical properties. To optimize their mechanical properties, here a novel Fe–Ni–P/porou...
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Article
Open AccessSpontaneous ventilation anesthesia combined with uniportal and tubeless thoracoscopic sympathectomy in selected patients with primary palmar hyperhidrosis
To assess the feasibility and safety of tubeless video-assisted thoracoscopic sympathectomy (VATS) with a single 5 mm port under nonintubated, intravenous anesthesia with spontaneous ventilation in selected pa...
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Article
Open AccessMetabolic tuning of a stable microbial community in the surface oligotrophic Indian Ocean revealed by integrated meta-omics
Understanding the mechanisms, structuring microbial communities in oligotrophic ocean surface waters remains a major ecological endeavor. Functional redundancy and metabolic tuning are two mechanisms that have...
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Article
Open AccessAssociations between thyroid function and gestational diabetes mellitus in Chinese pregnant women: a retrospective cohort study
Thyroid function is known to be closely linked with type 2 diabetes, but data on the association between thyroid function and gestational diabetes mellitus (GDM) are inconsistent.
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Article
Open AccessThe role of ceRNA-mediated diagnosis and therapy in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide due to its high degree of malignancy, high incidence, and low survival rate. However, the underlying mechanisms of ...
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Article
Open AccessNR4A3 and CCL20 clusters dominate the genetic networks in CD146+ blood cells during acute myocardial infarction in humans
CD146 is a tight junction-associated molecule involved in maintaining endothelial barrier, and balancing immune–inflammation response, in cardiovascular disease. Notably, peripheral CD146+ cells significantly ups...
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Article
Open AccessImpact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled trial
Dexmedetomidine promotes normal sleep architecture; the drug also improves analgesia. We therefore tested the hypothesis that supplementing intravenous analgesia with dexmedetomidine reduces delirium in older ...
