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Article
miR-124 represses FZD5 to attenuate P-glycoprotein-mediated chemo-resistance in renal cell carcinoma
Renal cell carcinoma (RCC) is one of most malignant neoplasms, exhibiting poor responsiveness to the conventional chemo-regime. Abnormal expression of P-glycoprotein (P-gp) has been implicated in the emergence...
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Article
Specific survivin dual fluorescence resonance energy transfer molecular beacons for detection of human bladder cancer cells
Survivin molecular beacons can be used to detect bladder cancer cells in urine samples non-invasively. The aim of this study is to improve the specificity of detection of bladder cancer cells using survivin du...
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Article
Upregulation of human DNA binding protein A (dbpA) in gastric cancer cells
To determine the effect of human DNA binding protein (dbpA) on the biology of gastric cancer cells.
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Article
Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression
Silibinin is known to exert growth inhibition and cell death together with cell cycle arrest and apoptosis in human prostate cancer cells. Whether silibinin could inhibit the invasion, motility and migration o...
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Article
Differentiations of transplanted mouse spermatogonial stem cells in the adult mouse renal parenchyma in vivo
Spermatogonial stem cells can initiate the process of cellular differentiation to generate mature spermatozoa, but whether it possess the characteristic of pluripotency and plasticity, similar to embryonic ste...
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Article
A novel anti-cancer effect of genistein: reversal of epithelial mesenchymal transition in prostate cancer cells
The aim of the present study was to investigate whether low dose genistein affects the invasion and epithelial mesenchymal transition (EMT) of prostate cancer (PCa) cells.
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Article
Effect of long-term partial bladder outlet obstruction on caldesmon isoforms and their correlation with contractile function
In the present study, we investigate the expression of caldesmon (CAD) isoforms in rabbit detrusor smooth muscles (DSM) during the progression of partial bladder outlet obstruction and relate them with the tim...
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Article
Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells
The aim of the present study was to investigate the effects of silencing the livin gene by small interfering RNA (siRNA) on the expression of livin and the effects on apoptosis, cell cycle, and proliferation i...
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Article
Overexpression of coxsackie and adenovirus receptor inhibit growth of human bladder cancer cell in vitro and in vivo
To study the effect of the overexpression of coxsackie and the adenovirus receptor (CAR) on the growth of the human bladder cancer cell in vitro and in vivo.
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Article
Transfection of promyelocytic leukemia in retrovirus vector inhibits growth of human bladder cancer cells
To construct a recombinant retrovirus vector carrying human promyelocytic leukemia (PML) cDNA and identify its expression and biology role in bladder cancer UM-UC-2 cells for future gene therapy.