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Article
Fruquintinib plus paclitaxel versus placebo plus paclitaxel for gastric or gastroesophageal junction adenocarcinoma: the randomized phase 3 FRUTIGA trial
The vascular endothelial growth factor pathway plays a key role in the pathogenesis of gastric cancer. In the multicenter, double-blind phase 3 FRUTIGA trial, 703 patients with advanced gastric or gastroesopha...
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Article
Deformation and stability analysis of the ancient Da’ao landslide revealed by InSAR and model simulation
Recurrence of large-scale ancient landslides often manifests as catastrophic events, so it is important to assess their stability by monitoring the deformation process. In this study, the Da’ao ancient landsli...
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Article
Open AccessUrban irrigation reduces moist heat stress in Bei**g, China
Although urban irrigation can modulate local hydrothermal conditions and mitigate urban heat island effects, its impact on moist heat stress (MHS) is poorly understood. Employing the Weather Research and Forec...
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Article
Gap between knowledge and action: understanding the consistency of farmers’ ecological cognition and green production behavior in Hainan Province, China
The pivotal role of greening production methods is indispensable in facilitating the sustainable development of China’s agricultural sector and its modernization process. Translating farmers’ ecological cognit...
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Article
Co-adsorption mechanisms of As(V) and Cd(II) by three-dimensional flower-like Mg/Al/Fe-CLDH synthesized by “memory effect”
Due to the different physical and chemical properties such as surface charge and ion morphology between As(V) and Cd(II), it is challenging to remove As(V) and Cd(II), especially at low concentrations. This st...
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Article
Inspired by Tree Frog: Bionic Design of Tread Pattern and Its Wet Friction Properties
The wet grip of tire has always been the focus because it is related to the personal safety of passengers directly. Many methods were employed to improve the wet grip of tire. Researchers paid more attention o...
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Article
Open AccessP2Y2 promotes fibroblasts activation and skeletal muscle fibrosis through AKT, ERK, and PKC
Skeletal muscle atrophy and fibrosis are pathological conditions that contribute to morbidity in numerous conditions including aging, cachexia, and denervation. Muscle atrophy is characterized as reduction of ...
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Article
Open AccessA phase I study of the safety and activity of K-001 in patients with advanced pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease that lack of effective therapeutic drugs. K-001 is an oral antitumor drug made from active ingredients of marine microorganisms. The current study ai...
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Article
Image real-time augmented reality technology based on spatial color and depth consistency
Augmented reality can enhance people’s perception of the environment by embedding virtual objects or other information in real-time images. In this paper, the color image is used as a reference to calculate th...
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Article
Safety Profile and Adverse Events of Special Interest for Fruquintinib in Chinese Patients with Previously Treated Metastatic Colorectal Cancer: Analysis of the Phase 3 FRESCO Trial
In FRESCO (Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients) trial, fruquintinib demonstrated a statistically significant and clinically meaningful overall survival benefit in Chinese pat...
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Article
Erratum to: Facile Fabrication of Biomimetic Water Pinning Microstructures on Polyethylene Surfaces with Robust Superhydrophobic Wetting State
The title was incorrect in the published paper and should be revised as “Facile Fabrication of Biomimetic Water Pinning Microstructures on Polyethylene Surfaces with Robust Superhydrophobic Wetting State”.
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Article
Titanium Ions Play a Synergistic Role in the Activation of NLRP3 Inflammasome in Jurkat T Cells
Release of titanium ions (Ti ions) frequently occurs around dental implants and, as a consequence, higher content of Ti is typically present in peri-implantitis tissue. Unlike chronic periodontitis, Ti ions ma...
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Article
Bionic Design to Reduce Jacking Force for Trenchless Installations in Clay Soil
The application of trenchless technology is the trend of underground public facilities’ installation, replacement and repairing. As the soil-engaging component during penetrating bore, the working resistance o...
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Article
Open AccessFacile Fabrication of Biomimetic Water Pinning Microstructures on Polyethylene Surfaces with Robust Superhydrophobic Wetting State
Applying hot-embossing technology, a simple and cost-effective method for the fabrication of microstructured High Density Polyethylene (HDPE) surfaces with a robust superhydrophobic wetting state is proposed. ...
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Article
Carbon emissions in the transportation sector of Yangtze River Economic Belt: decoupling drivers and inequality
Carbon emissions in the transportation sector are of great concern, since they are the third leading contributor to China’s carbon emissions. This research examines the decoupling relationship between economic...
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Article
A20 Restores Impaired Intestinal Permeability and Inhibits Th2 Response in Mice with Colitis
The etiology of inflammatory bowel disease is multifactorial and still obscure. The protective role of ubiquitin E3 ligase A20 (A20) in colitis needs to be further elucidated. This study aimed to investigate w...
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Article
The Tibetan Plateau Surface-Atmosphere Coupling System and Its Weather and Climate Effects: The Third Tibetan Plateau Atmospheric Science Experiment
The Tibetan Plateau (TP) is a key area affecting forecasts of weather and climate in China and occurrences of extreme weather and climate events over the world. The China Meteorological Administration, the Nat...
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Chapter and Conference Paper
Wide and Recurrent Neural Networks for Detection of False Data Injection in Smart Grids
A smart grid is a complex system using power transmission and distribution networks to connect electric power generators to consumers across a large geographical area. Due to their heavy dependencies on inform...
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Article
Erratum to: Bionic Optimization Design of Electronic Nose Chamber for Oil and Gas Detection
The first affiliation of the first author was incorrect in the published paper and should be revised as “1. College of Biological and Agricultural Engineering, Jilin University, Changchun 130022, China”.
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Article
An Optimal Wet Friction Plate Inspired by Biological Surface Patterns
It is found that many biological organisms exhibit superior adhesion characteristics in wet environments. It has been observed that the foot pads of tree frogs and katydids are consist of a number of closely a...