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  1. No Access

    Article

    Growth inhibition of experimental glioma grafts by monoclonal antibody treatment

    The effects of 14AC1 monoclonal antibody (McAb) on 79FR-G-41 rat glioma cells in vitro, on the formation of metastases in lung by antibody coated glioma cells, and on the growth of glioma grafts in BALB/c-nu/n...

    D. Stavrou, W. Mellert, U. Mellert… in Journal of Cancer Research and Clinical On… (1986)

  2. Article

    Monoclonal antibodies against huma gliomas

    K. Straemmler, D. Stavrou, H. Glässner… in Journal of Cancer Research and Clinical On… (1986)

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  3. No Access

    Article

    Presence and absence of virus particles in hybridomas secreting monoclonal antibodies against gliomas

    Hybridoma clones were produced by fusion of splenocytes from glioma-immunized hosts and the X63-Ag8.653 mouse myeloma line and Y3-Ag.1.2.3. rat myeloma line. Oncornavirus particles were found in all clones des...

    D. Stavrou, T. Bilzer, T. Tsangaris, E. Dürr… in Journal of Cancer Research and Clinical On… (1983)

  4. Article

    Phenotypic properties of neoplastic cell lines developed from fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo

    We have recently reported that fetal BD IX-rat brain cells (FBC), transferred to long-term culture after a transplacental pulse of EtNU on the 18th day of gestation, undergo neoplastic transformation in vitro ...

    O. D. Laerum, M. F. Rajewsky, M. Schachner… in Zeitschrift für Krebsforschung und Klinisc… (1977)

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    Article

    Gastroonkogene Wirkung von Methylnitrosoharnstoff beim Miniaturschwein

    The oncogenic effect of N-methyl-N-nitrosourea was studied in Hanford miniature-pig. The compound - dissolved in 0,9% NaC1 (pH 6,1 – 6,2) and supplemented with 1% NaH2PO4 - was administered per os to the animals ...

    D. Stavrou, E. Dahme, J. Kalich in Research in Experimental Medicine (1976)

  6. No Access

    Article

    Oncogene Wirkung von Äthylnitrosoharnstoff beim Kaninchen während der pränatalen Periode

    50 mg/kg ethylnitrosourea (ENU) per dose, diluted in a 0.9%NaCl/1%NaH2PO4 solution (pH 6.2) were administered intravenously to three pregnant rabbits. The injections were carried out on the following days of gest...

    D. Stavrou, T. Hänichen, I. Wriedt-Lübbe in Zeitschrift für Krebsforschung und Klinisc… (1975)

  7. No Access

    Article

    Immunhistochemischer Nachweis des hirnspezifischen S-100-Proteins bei experimentellen Hirntumoren

    In 50 adult Sprague-Dawley rats 42 neurogenic tumours were induced by oral application of 5 mg/kg N-methyl-N-nitrosourea through drinking water (pH 6.2). Out of this series 12 brain tumours have been set for in v...

    D. Stavrou, K. G. Haglid, H. Zankl… in Zeitschrift für Krebsforschung und Klinisc… (1974)

  8. No Access

    Article

    The presence of the S-100 protein in methylnitrosourea induced tumors of the nervous system in dogs

    The glia-specific protein S-100 has been demonstrated quantitatively in 1-methyl-1-nitrosourea-induced tumors of the dog CNS and PNS, which is a strong evidence for the neurooncogenic effect of MNU in the dog.

    D. Stavrou, K. G. Haglid in Research in Experimental Medicine (1974)

  9. No Access

    Article

    Alkylation of porcine nucleic acids following intravenous and intragastric application of N-methyl-N-nitrosourea

    Alkylation of nucleic acids was measured 3 h after the administration of N-(14C)-methyl-N-nitrosourea (10 mg/kg) to Hanford mini pigs. After intravenous injection the amount of 7-methylguanine formed in DNA and R...

    P. Kleihues, D. Stavrou, E. Scharrer… in Zeitschrift für Krebsforschung und Klinisc… (1973)

  10. No Access

    Article

    Water soluble proteins from rat brain and from experimental tumors of rat nervous system

    Disc electrophoretic separation of soluble proteins of rat brain and experimental tumors of the rat nervous system were performed in 10% polyacrylamide gels. As judged on the basis of relative mobilities, diff...

    D. Stavrou, K. G. Haglid in Zeitschrift für Krebsforschung und Klinische Onkologie (1973)

  11. No Access

    Article

    Bedeutung der Histotopochemie und des Isoenzymmusters der Lactatdehydrogenase für die Beurteilung der Dignität von Hirntumoren

    In the present study the topochemical distribution of lactate dehydrogenase (LDH) as well as the electrophoretic characteristics of their isoenzymes of 84 human brain tumors and 12 experimental rat gliomas wer...

    D. Stavrou, K. Zänker, W. Weidenbach… in Zeitschrift für Krebsforschung und Klinisc… (1973)

  12. No Access

    Article

    The brain specific proteins S100 and 14.3.2 in experimental brain tumors of the rat

    Primary tumors of the nervous system in rats induced by weekly administration of 6 mg/kg N-methylnitrosourea and spontaneous human brain tumors were investigated comparatively using immunoprecipitation techniq...

    D. Stavrou, K. G. Haglid, W. Weidenbach in Zeitschrift für die gesamte experimentelle… (1971)

  13. No Access

    Article

    Aktivität und Isoenzymmuster der Lactatdehydrogenase bei experimentellen Tumoren des peripheren Nervensystems der Ratte

    94 malignant schwannomas were induced in 200 rats by application of phenyl-dimethyl-triacene or 1-methyl-1-nitrosourea respectively. In 22 cases the tumors were analysed histochemically and electrophoretically...

    D. Stavrou, M. Knedel, H. Kirzeder in Zeitschrift für die gesamte experimentelle… (1970)

  14. No Access

    Article

    Zur Morphologie und Histochemie experimentell induzierter Hirntumoren beim Kaninchen

    Brain tumours, induced by intravenous application of 10 mg/kg 1-Methyl-1-nitrosourea in chinchilla rabbits, were classified as isomorph gliomas (oligodendroglioma I, II and glioblastoma), primary heteromorph g...

    D. Stavrou in Zeitschrift für Krebsforschung (1969)