-
Article
Open AccessModulation of fear extinction processes using transcranial electrical stimulation
Research associates processes of fear conditioning and extinction with treatment of anxiety and stress-related disorders. Manipulation of these processes may therefore be beneficial for such treatment. The cur...
-
Article
Open AccessDisentangling the autism−anxiety overlap: fMRI of reward processing in a community-based longitudinal study
Up to 40% of youth with autism spectrum disorder (ASD) also suffer from anxiety, and this comorbidity is linked with significant functional impairment. However, the mechanisms of this overlap are poorly unders...
-
Article
Anxiety in childhood across the globe: findings from meta-regression analyses of the past 15 years (1998–2013)
-
Article
Extreme early-life anxiety is associated with an evolutionarily conserved reduction in the strength of intrinsic functional connectivity between the dorsolateral prefrontal cortex and the central nucleus of the amygdala
-
Article
Evolutionarily conserved prefrontal-amygdalar dysfunction in early-life anxiety
Some individuals are endowed with a biology that renders them more reactive to novelty and potential threat. When extreme, this anxious temperament (AT) confers elevated risk for the development of anxiety, de...
-
Article
Open AccessEarly childhood temperament predicts substance use in young adults
Behavioral inhibition (BI) is an important early childhood marker of risk for later psychiatric problems. The current 20-year prospective, longitudinal study focused on individual differences in this early tem...
-
Article
A latent modeling approach to genotype–phenotype relationships: maternal problem behavior clusters, prenatal smoking, and MAOA genotype
This study illustrates the application of a latent modeling approach to genotype–phenotype relationships and gene × environment interactions, using a novel, multidimensional model of adult female problem behav...
-
Article
Interaction of prenatal exposure to cigarettes and MAOA genotype in pathways to youth antisocial behavior
Genetic susceptibility to antisocial behavior may increase fetal sensitivity to prenatal exposure to cigarette smoke. Testing putative gene × exposure mechanisms requires precise measurement of exposure and ou...
-
Article
Le modèle triadique des aspects neurobiologiques des comportements motivés à l’adolescence
Le comportement de prise de risque est une cause majeure de morbidité et de mortalité à l’adolescence. Dans le contexte d’une théorie de la décision et des comportements motivés (c’est-à-dire dirigé vers un bu...
-
Article
Depressive symptoms during childhood and adult obesity: the Zurich Cohort Study
Depression and obesity have become major health problems with increasing prevalence. Given the limited effectiveness of treatment for weight problems, the identification of novel, potentially modifiable risk f...
