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Article
Combination of immunoglobulins and natural killer cells in the context of CMV and EBV infection
Cytomegalovirus (CMV)-specific hyperimmunoglobulin (CMV-HIG) is used to treat and prevent CMV infection in immunocompromised patients, and anti-CD20 monoclonal antibody is successfully used in the treatment fo...
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Article
Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell lines
Primary infection and reactivation of human cytomegalovirus (CMV) remain a major problem in immunocompromised patients, frequently resulting in a life threatening CMV disease. Intravenous polyvalent (hyper)-im...
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Article
First Molecular Evidence for Puumala Hantavirus in Slovakia
We report on the first Puumala hantavirus nucleotide sequence (strain Opina-916) amplified from a bank vole trapped in Slovakia, central Europe. Phylogenetic analysis of the S-segment sequence grouped the viru...
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Article
Coding strategy of the S and M genomic segments of a hantavirus representing a new subtype of the Puumala serotype
The hantavirus strain Vranica was previously reported to have been isolated from a bank vole in Bosnia-Hercegovina and associated with the occurrence of hemorrhagic fever with renal syndrome (HRFS) in humans. ...
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Article
Fine map** of HIV-1 Nef-epitopes by monoclonal antibodies
A panel of newly isolated murine monoclonal antibodies is described which are specific for the Nef protein of the human immunodeficiency virus type 1 (HIV-1). Epitope map** using recombinant Nef-related prot...
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Article
Immunogenicity of recombinant core particles of hepatitis B virus containing epitopes of human immunodeficiency virus 1 core antigen
A Gag protein segment of human immunodeficiency virus 1 (HIV-1) has been fused to a C terminally truncated core antigen of hepatitis B virus (HBcAg) using anE. coli expression system. Fusion of 90 amino acids of ...
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Article
Mutations in the hemagglutinin gene associated with influenza virus resistance to norakin
The nucleotide sequences of the hemagglutinin genes of four norakinresistant mutants of Influenza A/FPV/Weybridge were determined and compared to the wild-type hemagglutinin. All mutants show one or two amino ...