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Article
Combination of immunoglobulins and natural killer cells in the context of CMV and EBV infection
Cytomegalovirus (CMV)-specific hyperimmunoglobulin (CMV-HIG) is used to treat and prevent CMV infection in immunocompromised patients, and anti-CD20 monoclonal antibody is successfully used in the treatment fo...
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Article
Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell lines
Primary infection and reactivation of human cytomegalovirus (CMV) remain a major problem in immunocompromised patients, frequently resulting in a life threatening CMV disease. Intravenous polyvalent (hyper)-im...
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Article
Detection of Human Hantavirus Infections in Lithuania
In Europe certain hantaviruses are known to cause hemorrhagic fever with renal syndrome of different severity. The objective of the present investigation was to study the presence of hantavirus infections in L...
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Chapter
A Nomenclature for Restriction Enzymes, DNA Methyltransferases, Homing Endonucleases, and Their Genes
There are three main groups of restriction endonucleases (REases) called Types I, II, and III (1,2). Since 1973, REases and DNA methyltransferases (MTases) have been named based on an original suggestion by Sm...
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Chapter
Structure and Function of Type IIE Restriction Endonucleases — or: From a Plasmid That Restricts Phage Replication to A New Molecular DNA Recognition Mechanism
Restriction endonucleases (REases) and DNA methyltransferases (MTases) are encoded by chromosomal, plasmid, or viral genes. In eubacteria as well as in archaea, they often form biologically active DNA restrict...
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Article
First Molecular Evidence for Puumala Hantavirus in Slovakia
We report on the first Puumala hantavirus nucleotide sequence (strain Opina-916) amplified from a bank vole trapped in Slovakia, central Europe. Phylogenetic analysis of the S-segment sequence grouped the viru...
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Article
Primary hepatic or splenic diffuse large B-cell lymphoma and hepatitis C virus infection: a non-fortuitous association?
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Article
Disappearance of hepatitis B virus core deletion mutants and successful combined kidney/liver transplantation in a patient treated with lamivudine
Hepatitis B virus (HBV) core deletion variants with enhanced viral replication are associated with rapid deterioration of liver function in renal allograft recipients. Antiviral agents such as famciclovir and...
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Article
First Case of Infection with Hantavirus Dobrava in Germany
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Article
Abstracts of presentations on plant protection issues at the fifth international Mango Symposium Abstracts of presentations on plant protection issues at the Xth international congress of Virology
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Article
The use of polymerase chain reaction (PCR) in the detection and characterization of HBV variants
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Article
Diagnostic value of human cytomegalovirus DNA PCR regarding different clinical specimens
In transplant recipients, a positive HCMV PCR in PBLs is a sign of the possible development of HCMV disease which should be confirmed by further diagnostic approaches. However, detection of HCMV DNA in the CSF...
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Article
Detection of hantaviruses by polymerase chain reaction
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Article
Coding strategy of the S and M genomic segments of a hantavirus representing a new subtype of the Puumala serotype
The hantavirus strain Vranica was previously reported to have been isolated from a bank vole in Bosnia-Hercegovina and associated with the occurrence of hemorrhagic fever with renal syndrome (HRFS) in humans. ...
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Article
Seroprevalence of hantavirus antibodies in Germany as determined by a new recombinant enzyme immunoassay
In order to elucidate the epidemiological importance of hemorrhagic fever with renal syndrome in Germany, the prevalence of antibodies against hantaviruses was determined in 13,358 sera from residents of vario...
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Article
Fine map** of HIV-1 Nef-epitopes by monoclonal antibodies
A panel of newly isolated murine monoclonal antibodies is described which are specific for the Nef protein of the human immunodeficiency virus type 1 (HIV-1). Epitope map** using recombinant Nef-related prot...
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Article
Immunogenicity of recombinant core particles of hepatitis B virus containing epitopes of human immunodeficiency virus 1 core antigen
A Gag protein segment of human immunodeficiency virus 1 (HIV-1) has been fused to a C terminally truncated core antigen of hepatitis B virus (HBcAg) using anE. coli expression system. Fusion of 90 amino acids of ...
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Article
Avoidance of DNA methylation
Theocr + gene of bacterial virus T7 codes for the first protein recognized to inhibit a specific group of DNA methylases. The recognition sequences of several other DNA methylases, not susceptible...
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Article
Mutations in the hemagglutinin gene associated with influenza virus resistance to norakin
The nucleotide sequences of the hemagglutinin genes of four norakinresistant mutants of Influenza A/FPV/Weybridge were determined and compared to the wild-type hemagglutinin. All mutants show one or two amino ...
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Article
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