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Article
Combination of immunoglobulins and natural killer cells in the context of CMV and EBV infection
Cytomegalovirus (CMV)-specific hyperimmunoglobulin (CMV-HIG) is used to treat and prevent CMV infection in immunocompromised patients, and anti-CD20 monoclonal antibody is successfully used in the treatment fo...
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Article
Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell lines
Primary infection and reactivation of human cytomegalovirus (CMV) remain a major problem in immunocompromised patients, frequently resulting in a life threatening CMV disease. Intravenous polyvalent (hyper)-im...
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Article
First Molecular Evidence for Puumala Hantavirus in Slovakia
We report on the first Puumala hantavirus nucleotide sequence (strain Opina-916) amplified from a bank vole trapped in Slovakia, central Europe. Phylogenetic analysis of the S-segment sequence grouped the viru...
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Article
First Case of Infection with Hantavirus Dobrava in Germany
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Article
Coding strategy of the S and M genomic segments of a hantavirus representing a new subtype of the Puumala serotype
The hantavirus strain Vranica was previously reported to have been isolated from a bank vole in Bosnia-Hercegovina and associated with the occurrence of hemorrhagic fever with renal syndrome (HRFS) in humans. ...
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Article
Seroprevalence of hantavirus antibodies in Germany as determined by a new recombinant enzyme immunoassay
In order to elucidate the epidemiological importance of hemorrhagic fever with renal syndrome in Germany, the prevalence of antibodies against hantaviruses was determined in 13,358 sera from residents of vario...
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Article
Fine map** of HIV-1 Nef-epitopes by monoclonal antibodies
A panel of newly isolated murine monoclonal antibodies is described which are specific for the Nef protein of the human immunodeficiency virus type 1 (HIV-1). Epitope map** using recombinant Nef-related prot...
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Article
Immunogenicity of recombinant core particles of hepatitis B virus containing epitopes of human immunodeficiency virus 1 core antigen
A Gag protein segment of human immunodeficiency virus 1 (HIV-1) has been fused to a C terminally truncated core antigen of hepatitis B virus (HBcAg) using anE. coli expression system. Fusion of 90 amino acids of ...
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Article
Mutations in the hemagglutinin gene associated with influenza virus resistance to norakin
The nucleotide sequences of the hemagglutinin genes of four norakinresistant mutants of Influenza A/FPV/Weybridge were determined and compared to the wild-type hemagglutinin. All mutants show one or two amino ...