Skip to main content

2 Result(s)

within D. E. Martens Remove this filter Biomedicine Remove this filter

and

  1. No Access

    Chapter

    To an Optimal Design of an Airlift Bioreactor for the Cultivation of Hybridomas

    One of the main problems in scaling up hybridoma cell cultures is the supply of oxygen, since sparging and agitation can lead to excessive cell death. This study concerns the relation between the air flow and ...

    D. E. Martens, Martin J. Coco, Cam van der Velden-De Groot… in From Clone to Clinic (1990)

  2. No Access

    Chapter

    Development of Analytical Methods for Monitoring the Stability of Antibody Formation by Hybridoma Cells in Continuous Culture Systems

    In this study an isotype specific spot-ELISA and two flow cytometric analytical procedures (FC) have been developed. Furthermore, we used different ELISA systems and isoelectric focusing (IEF) for analysis of ...

    J. M. Coco Martin, P. Koolwijk, D. E. Martens, J. W. Oberink… in From Clone to Clinic (1990)