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Article
Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling
T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive neoplasm of mature T-cells with an urgent need for rationally designed therapies to address its notoriously chemo-refractory behavior. The median...
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Article
Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia
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Article
MiR-30a-5p connects EWS-FLI1 and CD99, two major therapeutic targets in Ewing tumor
Ewing sarcoma is a pediatric bone tumor characterized in 85% of cases by the fusion between EWS and FLI1 genes that results in the expression of the EWS-FLI1 aberrant transcription factor. Histologically, the Ewi...
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Article
Tissue attachment strength of prosthetic meshes used in ventral and incisional hernia repair
Background: Many prosthetic materials are used in incisional hernia repair, including polypropylene (PP) and expanded polytetrafluoroethylene (ePTFE). However, PP forms severe adhesions and ePTFE has raised co...