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Article
Open AccessAbundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study
Genetic pleiotropy is abundant across spatially distributed brain characteristics derived from one neuroimaging modality (e.g. structural, functional or diffusion magnetic resonance imaging [MRI]). A better un...
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Article
Open AccessPredicting attention-deficit/hyperactivity disorder severity from psychosocial stress and stress-response genes: a random forest regression approach
Identifying genetic variants contributing to attention-deficit/hyperactivity disorder (ADHD) is complicated by the involvement of numerous common genetic variants with small effects, interacting with each othe...
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Article
Open AccessAdolescent behavioral and neural reward sensitivity: a test of the differential susceptibility theory
Little is known about the causes of individual differences in reward sensitivity. We investigated gene–environment interactions (GxE) on behavioral and neural measures of reward sensitivity, in light of the di...
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Article
Combined stimulant and antipsychotic treatment in adolescents with attention-deficit/hyperactivity disorder: a cross-sectional observational structural MRI study
Meta-analyses suggest normalizing effects of methylphenidate on structural fronto-striatal abnormalities in patients with attention-deficit/hyperactivity disorder (ADHD). A subgroup of patients receives atypi...
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Chapter and Conference Paper
From Granular Flux Model to Traffic Flow Description
A description of highway traffic flow is proposed, based on a flux model originally developed for granular gases in a compartmentalized setup. Results from a pilot study of the highway A58 in the Netherlands a...