4 Result(s)

Article

Hereditary and non-hereditary branches of family eligible for BRCA test: cancers in other sites

The analysis of relationships of BRCA alterations with cancer at sites other than breast/ovary may provide innovative information concerning BRCA pathogenic role and support additional clinical decisions. Aim ...

M. Digennaro, D. Sambiasi, S. Tommasi, B. Pilato… in Hereditary Cancer in Clinical Practice (2017)

Article

Comment on ‘The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study’

A V Paradiso, M Digennaro, D Sambiasi in British Journal of Cancer (2016)

Article

Expression of base excision repair key factors and miR17 in familial and sporadic breast cancer

Understanding of BRCA1/2 interaction with the base excision repair (BER) pathway could improve therapy based on ‘synthetic lethality’, whose effectiveness is based on homologous recombination deficiency in cel...

S De Summa, R Pinto, B Pilato, D Sambiasi, L Porcelli, G Guida… in Cell Death & Disease (2014)

Article

Phase I/II study of gemcitabine plus mitoxantrone as salvage chemotherapy in metastatic breast cancer

The purpose of this study was to determine the maximum-tolerated dose of gemcitabine plus mitoxantrone in women with metastatic breast cancer (MBC) and to evaluate activity and toxicity of this combination in ...

V Lorusso, E Crucitta, N Silvestris, A Catino, L Caporusso… in British Journal of Cancer (2003)