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  1. Article

    Open Access

    Thermo-sensitive hydrogels combined with decellularised matrix deliver bFGF for the functional recovery of rats after a spinal cord injury

    Because of the short half-life, either systemic or local administration of bFGF shows significant drawbacks to spinal injury. In this study, an acellular spinal cord scaffold (ASC) was encapsulated in a thermo...

    He-Lin Xu, Fu-Rong Tian, Cui-Tao Lu, Jie Xu, Zi-Liang Fan… in Scientific Reports (2016)

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  2. Article

    Using PG-Liposome-Based System to Enhance Puerarin Liver-Targeted Therapy for Alcohol-Induced Liver Disease

    A critical issue for alcohol-induced liver disease (ALD) therapeutics is the lack of a highly efficient delivery system. In this study, a Puerarin-propylene glycol-liposome system was prepared for the purpose ...

    Ying-Zheng Zhao, Lu Zhang, Pardeep K. Gupta, Fu-Rong Tian, Kai-Li Mao… in AAPS PharmSciTech (2016)

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  3. No Access

    Article

    Advanced Interfere Treatment of Diabetic Cardiomyopathy Rats by aFGF-Loaded Heparin-Modified Microbubbles and UTMD Technique

    This study aims to investigate the preclinical performance and mechanism of a novel strategy of aFGF-loaded heparin-modified microbubbles (aFGF-HMB) combined with ultrasound-targeted microbubble destruction (U...

    Ming Zhang, Wen-Ze Yu, **ao-Tong Shen, Qi **ang, Jie Xu… in Cardiovascular Drugs and Therapy (2016)

  4. No Access

    Article

    Brain tumor-targeted delivery and therapy by focused ultrasound introduced doxorubicin-loaded cationic liposomes

    Brain tumor lacks effective delivery system for treatment. Focused ultrasound (FUS) can reversibly open BBB without impacts on normal tissues. As a potential drug carrier, cationic liposomes (CLs) have the ab...

    Qian Lin, Kai-Li Mao, Fu-Rong Tian, **g-**g Yang… in Cancer Chemotherapy and Pharmacology (2016)

  5. No Access

    Article

    Experiment on the feasibility of using modified gelatin nanoparticles as insulin pulmonary administration system for diabetes therapy

    Polymeric nanoparticles are widely used as targeted carriers for biomacromolecules. In this paper, modified gelatin nanoparticles were prepared and their feasibility as insulin pulmonary administration system ...

    Ying-Zheng Zhao, **ng Li, Cui-Tao Lu, Yan-Yan Xu, Hai-Feng Lv… in Acta Diabetologica (2012)

  6. No Access

    Article

    Experiment on enhancing antitumor effect of intravenous epirubicin hydrochloride by acoustic cavitation in situ combined with phospholipid-based microbubbles

    An in vivo study on enhancing antitumor effect of intravenous epirubicin hydrochloride (EPI) by acoustic cavitation in situ combined with phospholipid-based microbubbles (PMB) was reported.

    Cui-Tao Lu, Ying-Zheng Zhao, Yan Wu, **n-Qiao Tian… in Cancer Chemotherapy and Pharmacology (2011)

  7. No Access

    Article

    Factors that affect the efficiency of antisense oligodeoxyribonucleotide transfection by insonated gas-filled lipid microbubbles

    Objective: To investigate the factors that affect the efficiency of antisense oligodeoxyribonucleotide(AS-ODNs) transfection by insonated gas-filled lipid microbubbles. Methods: Lipid mic...

    Ying-Zheng Zhao, Cui-Tao Lu in Journal of Nanoparticle Research (2008)

  8. No Access

    Article

    Improvement of phenylethanoid glycosides production by a fungal elicitor in cell suspension culture of Cistanche deserticola

    When, on the 15th day of growth, an elicitor from Fusarium solani was added at 40 mg l−1 to Cistanche deserticola cell suspension cultures, the contents of echinacoside, acteoside and total phenylethanoid glycosi...

    Cui-tao Lu, **ng-guo Mei in Biotechnology Letters (2003)

  9. No Access

    Article

    Improved paclitaxel accumulation in cell suspension cultures of Taxus chinensis by brassinolide

    When brassinolide was added at 17 ng l−1 to Taxus chinensis cell suspension cultures, the paclitaxel content was increased by over 100% to 580 μg g−1 dry weight. Brassinolide may therefore be a novel regulator of...

    **n Zang, **ng-Guo Mei, Chang-He Zhang, Cui-Tao Lu, Tie Ke in Biotechnology Letters (2001)