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  1. Article

    Open Access

    Critical values and variation in type I error along chromosomes in the COGA dataset using the applied pseudo-trait method

    By analyzing a "pseudo-trait," a trait not linked or associated with any of the markers tested, the distribution of the test statistic under the null hypothesis can provide the critical value for the appropria...

    George J Papanicolaou, Cristina M Justice, Illija M Kovac, Alexa JM Sorant… in BMC Genetics (2005)

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  2. Article

    Open Access

    Comparison of year-of-exam- and age-matched estimates of heritability in the Framingham Heart Study data

    Several different approaches can be used to examine generational and temporal trends in family studies. The measurement of offspring and parents can be made over a short period of time with parents and offspri...

    Rasika A Mathias, Marie-Hélène Roy-Gagnon, Cristina M Justice… in BMC Genetics (2003)

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  3. No Access

    Article

    Phylogenetic Analysis of the Friedreich Ataxia GAA Trinucleotide Repeat

    Friedreich ataxia is an autosomal recessive neurodegenerative disorder associated with a GAA repeat expansion in the first intron of the gene (FRDA) encoding a novel, highly conserved, 210 amino acid protein ...

    Cristina M. Justice, Zhining Den, Son V. Nguyen… in Journal of Molecular Evolution (2001)