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Article
Open AccessOpportunities for personalised follow-up in breast cancer: the gap between daily practice and recurrence risk
Follow-up guidelines barely diverge from a one-size-fits-all approach, even though the risk of recurrence differs per patient. However, the personalization of breast cancer care improves outcomes for patients....
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Article
Open AccessFour-dimensional computed tomography as first-line imaging in primary hyperparathyroidism, a retrospective comparison to conventional imaging in a predominantly single adenoma population
To determine the use of four-dimensional CT as first-line imaging compared to the traditional combination of ultrasound and [99mTc]Tc-Sestamibi SPECT.
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Article
Development of an in vitro setup for flow studies in a stented carotid artery bifurcation
To investigate flow conditions in a double-layered carotid artery stent, a bench-top in vitro flow setup including a bifurcation phantom was designed and fabricated. The geometry of the tissue-mimicking phanto...
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Article
Open AccessDiagnostic value of regional myocardial flow reserve measurements using Rubidium-82 PET
Visual assessment of Rubidium (Rb-82) PET myocardial perfusion images is usually combined with global myocardial flow reserve (MFR) measurements. However, small regional blood flow deficits may go unnoticed. O...
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Article
Open Access[18F]FDG-PET/CT radiomics for the identification of genetic clusters in pheochromocytomas and paragangliomas
Based on germline and somatic mutation profiles, pheochromocytomas and paragangliomas (PPGLs) can be classified into different clusters. We investigated the use of [18F]FDG-PET/CT radiomics, SUVmax and biochemica...
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Article
Open AccessCorrection to: Development of a dedicated 3D printed myocardial perfusion phantom: proof-of-concept in dynamic SPECT
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Article
Open AccessDevelopment of a dedicated 3D printed myocardial perfusion phantom: proof-of-concept in dynamic SPECT
We aim to facilitate phantom-based (ground truth) evaluation of dynamic, quantitative myocardial perfusion imaging (MPI) applications. Current MPI phantoms are static representations or lack clinical hard- and...
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Article
Open AccessDevelopment of a dynamic myocardial perfusion phantom model for tracer kinetic measurements
Absolute myocardial perfusion imaging (MPI) is beneficial in the diagnosis and prognosis of patients with suspected or known coronary artery disease. However, validation and standardization of perfusion estima...
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Article
Open AccessAppearance of the levator ani muscle subdivisions on 3D transperineal ultrasound
The levator ani muscle (LAM) consists of different subdivisions, which play a specific role in the pelvic floor mechanics. The aim of this study is to identify and describe the appearance of these subdivisions...
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Article
Open AccessExperimental validation of absolute SPECT/CT quantification for response monitoring in patients with coronary artery disease
Quantitative SPECT enables absolute quantification of uptake in perfusion defects. The aim of this experimental study is to assess quantitative accuracy and precision of a novel iterative reconstruction techni...
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Article
Open AccessDay-to-day variability of [68Ga]Ga-PSMA-11 accumulation in primary prostate cancer: effects on tracer uptake and visual interpretation
Prostate-specific membrane antigen (PSMA) agents, such as [68Ga]Ga-PSMA-11, have an unprecedented accuracy in staging prostate cancer (PCa) and detecting disease recurrence. PSMA PET/CT may also be used for respo...
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Article
Open Access(In)comparability of Carotid Artery Stent Characteristics: A Systematic Review on Assessment and Comparison with Manufacturer Data
Carotid stent (CS) characteristics, such as radial force, scaffolding and flexibility, are continuously modified by stent manufacturers aiming to improve stent performance. Since manufacturers’ definitions and...
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Article
Open Access68Ga-PSMA Cerenkov luminescence imaging in primary prostate cancer: first-in-man series
Currently, approximately 11–38% of prostate cancer (PCa) patients undergoing radical prostatectomy have a positive surgical margin (PSM) on histopathology. Cerenkov luminescence imaging (CLI) using 68Ga-prostate-...
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Article
Open AccessEffect of irreversible electroporation parameters and the presence of a metal stent on the electric field line pattern
The final ablation zone created with irreversible electroporation (IRE) depends on the size, shape and strength of the electric field that is influenced by several parameters. A profound understanding of the e...
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Article
Open AccessAssessment of Dynamic Change of Coronary Artery Geometry and Its Relationship to Coronary Artery Disease, Based on Coronary CT Angiography
To investigate the relationship between dynamic changes of coronary artery geometry and coronary artery disease (CAD) using computed tomography (CT). Seventy-one patients underwent coronary CT angiography with...
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Article
Open AccessQuantitative imaging: systematic review of perfusion/flow phantoms
We aimed at reviewing design and realisation of perfusion/flow phantoms for validating quantitative perfusion imaging (PI) applications to encourage best practices.
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Article
Open AccessSUV variability in EARL-accredited conventional and digital PET
A high SUV-reproducibility is crucial when different PET scanners are in use. We evaluated the SUV variability in whole-body FDG-PET scans of patients with suspected or proven cancer using an EARL-accredited c...
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Article
Open AccessDiagnosing Internal Herniation After Roux-en-Y Gastric Bypass Surgery: Literature Overview, Cadaver Study and the Added Value of 3D CT Angiography
The purposes of the study are to outline the complexity of diagnosing internal herniation after Roux-en-Y gastric bypass (RYGB) surgery and to investigate the added value of computed tomography angiography (CT...
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Article
Open AccessDiagnostic implications of a small-voxel reconstruction for loco-regional lymph node characterization in breast cancer patients using FDG-PET/CT
We evaluated the diagnostic implications of a small-voxel reconstruction for lymph node characterization in breast cancer patients, using state-of-the-art FDG-PET/CT. We included 69 FDG-PET/CT scans from breas...
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Chapter and Conference Paper
Quantification of Macrocirculation and Microcirculation in Brain Using Ultrasound Perfusion Imaging
Objective: The aim of this study was to investigate the feasibility of simultaneous visualization of the cerebral macrocirculation and microcirculation, using ultrasound perfusion imaging (UPI). In addition, we ...
