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Article
Open AccessThird International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions)
The heterogeneous group of B3 lesions in the breast harbors lesions with different malignant potential and progression risk. As several studies about B3 lesions have been published since the last Consensus in ...
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Article
Open AccessBiomarker dynamics and prognosis in breast cancer after neoadjuvant chemotherapy
Breast cancer is a biologically diverse disease with treatment modalities selected based on tumor stage and tumor biology. Distinct intrinsic subtypes and surrogate biomarker profiles play a major role for the...
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Article
Open AccessDiscrepancies between radiological and histological findings in preoperative core needle (CNB) and vacuum-assisted (VAB) breast biopsies
Ultrasound (US)-guided breast biopsy is a routine diagnostic method used to correlate imaging finding to a histological diagnosis which is still the gold standard in preoperative diagnostics. The accuracy of U...
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Article
Open AccessBreast-conserving surgery with intraoperative radiotherapy in recurrent breast cancer: the patient’s perspective
When ipsilateral breast-tumor recurrence (IBTR) following breast-conserving surgery (BCS) occurs, the cure of a potentially life-threatening disease is the main goal. If, however, this is diagnosed early, prog...
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Article
Differential prognostic value of positive HER2 status determined by immunohistochemistry or fluorescence in situ hybridization in breast cancer
Human epidermal growth factor-receptor-2 (HER2) is a membrane-tyrosine-kinase that is amplified/overexpressed up to 20% in breast cancer. HER2 positive status is associated with faster disease progression, hig...
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Article
Noncompliance with palliative systemic therapy in patients with distant metastatic breast cancer: a blind spot for oncologists?
The goal of our study was to provide a general overview of noncompliance with palliative systemic therapy in distant metastatic breast cancer (MBC).