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Article

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC), the most prevalent type of pancreatic cancer, is one of the deadliest forms of cancer with limited therapy options. Overexpression of the heat shock protein 70 (HSP70) ...

Giulia D. S. Ferretti, Colleen E. Quaas, Irene Bertolini… in Cell Death & Differentiation (2024)