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Article
An updated model for predicting side-specific extraprostatic extension in the era of MRI-targeted biopsy
Accurate prediction of extraprostatic extension (EPE) is pivotal for surgical planning. Herein, we aimed to provide an updated model for predicting EPE among patients diagnosed with MRI-targeted biopsy.
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Article
The relative impact of lymph-node metastasis and seminal vesical invasion on oncologic outcomes following radical prostatectomy
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Article
Cumulative sum analysis (CUSUM) for evaluating learning curve (LC) of robotic-assisted laparoscopic partial nephrectomy (RALPN)
Robotic-assisted laparoscopic partial nephrectomy (RALPN) is becoming a standard treatment for localized renal tumors worldwide. Data on the learning curve (LC) of RALPN are still insufficient. In the present ...
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Article
Open AccessRisk and predictors of adverse pathology after radical prostatectomy in patients diagnosed with IUSP 1–2 prostate cancer at MRI-targeted biopsy: a multicenter analysis
Although active surveillance (AS) is recommended for low- to favorable intermediate-risk prostate cancer (PCa), risk of upgrading at radical prostatectomy (RP) is not negligible. Available studies based on sys...
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Article
Open AccessHigh fibroblast-activation-protein expression in castration-resistant prostate cancer supports the use of FAPI-molecular theranostics
To evaluate fibroblast-activation-protein (FAP) expression in different clinical stages of prostate cancer (PC) with regards to utility of [68 Ga]Ga-FAPI-04 PET/CT imaging in patients with castration-resistant PC...
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Article
A polymeric paste-drug formulation for intratumoral treatment of prostate cancer
Focal therapy has emerged as a treatment option for low- to intermediate-risk localized prostate cancer (PCa) patients, to balance the risks for urinary and sexual morbidity of radical treatment with the psych...
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Article
Multiple instance learning combined with label invariant synthetic data for guiding systematic prostate biopsy: a feasibility study
Ultrasound imaging is routinely used in prostate biopsy, which involves obtaining prostate tissue samples using a systematic, yet, non-targeted approach. This approach is blinded to individual patient intrapro...
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Article
Design and Characterization of Injectable Poly(Lactic-Co-Glycolic Acid) Pastes for Sustained and Local Drug Release
We describe the preparation of injectable polymeric paste (IPP) formulations for local and sustained release of drugs. Furthermore, we include the characterization and possible applications of such pastes. Par...
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Article
Open AccessCorrelation between genomic index lesions and mpMRI and 68Ga-PSMA-PET/CT imaging features in primary prostate cancer
Magnetic resonance imaging (MRI) and prostate specific membrane antigen (PSMA)- positron emission tomography (PET)/computed tomography (CT)-imaging of prostate cancer (PCa) are emerging techniques to assess th...
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Article
Prostate segmentation in MRI using a convolutional neural network architecture and training strategy based on statistical shape models
Most of the existing convolutional neural network (CNN)-based medical image segmentation methods are based on methods that have originally been developed for segmentation of natural images. Therefore, they lar...
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Article
Prostate segmentation in transrectal ultrasound using magnetic resonance imaging priors
In the current standard of care, real-time transrectal ultrasound (TRUS) is commonly used for prostate brachytherapy guidance. As TRUS provides limited soft tissue contrast, segmenting the prostate gland in TR...
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Article
Simultaneous whole-body 18F–PSMA-1007-PET/MRI with integrated high-resolution multiparametric imaging of the prostatic fossa for comprehensive oncological staging of patients with prostate cancer: a pilot study
The aim of the present study was to explore the clinical feasibility and reproducibility of a comprehensive whole-body 18F–PSMA-1007-PET/MRI protocol for imaging prostate cancer (PC) patients.
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Chapter
Multiparametric MRI and MRI/TRUS Fusion Guided Biopsy for the Diagnosis of Prostate Cancer
Purpose of this chapter To demonstrate the timing, benefits, limitations and current controversies of multiparametric magnet resonance imaging (mpMRI) combined with fusion guided biopsy and consider how addition...
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Chapter
Prostatakrebsdiagnostik: Die MRT-Ultraschall-Fusionsbiopsie
Prostatakrebs ist die häufigste Krebserkrankung bei Männern in Deutschland. Männern, bei denen eine verdächtige Verhärtung der Prostata ertastet oder bei denen ein erhöhter PSA-Wert festgestellt wurde, wird ei...
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Chapter
Imaging of the Large Prostate
The diagnostic and imaging workflow for patients with enlarged prostates is still unclear. In this abstract we elucidate the role of ultrasound and MRI in diagnostics and treatment follow-up for “the large pro...
