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Protocol
MT1 Receptor Signaling Pathways by Impedance Measurement
Melatonin exerts its classical effects of relay of the circadian rhythm through two G protein-coupled receptors, MT1 and MT2. The functions attributed to melatonin are so numerous that the action of this neuro...
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Protocol
Functionality of Melatonin Receptors: Recruitment of β-Arrestin at MT1
The main process of downregulation of G protein-coupled receptors is desensitization by which the receptor is extruded from the membrane and directed to the endosomal compartment for recycling. Typically, th...
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Protocol
Functionality of Melatonin Receptors: Internalization
The main step of classical desensitization of a receptor, by mean of its disappearance from the plasma membrane, is its internalization. This is a key factor in the regulation of agonist-mediated signaling pat...
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Article
Open AccessGene expression profiling during hibernation in the European hamster
Hibernation is an exceptional physiological response to a hostile environment, characterized by a seasonal period of torpor cycles involving dramatic reductions of body temperature and metabolism, and arousal ...
