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Article
Open AccessIdentification of gene expression biomarkers to predict clinical response to methotrexate in patients with rheumatoid arthritis
To identify biomarkers at the gene expression level to predict response to methotrexate (MTX) in patients with rheumatoid arthritis (RA).
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Article
Metabolic regulation of inflammation
Immune cells face a variety of variable and sometimes demanding environmental conditions, requiring them to display a dynamic range of metabolic adaptation pro...
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Article
Disentangling the effects of tocilizumab on neutrophil survival and function
The synovial tissue in rheumatoid arthritis (RA) represents a hypoxic environment with up-regulated pro-inflammatory cytokines and cellular infiltrates including neutrophils. Although inhibition of the interle...
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Article
High-Sensitivity Immunofluorescence Staining: A Comparison of the Liposome Procedure and the FASER Technique on mGR Detection
Flow cytometry has become a widely-used and powerful tool for the characterization of cells according to their expression of specific proteins. However, sensitivity of this method is still limited since conven...
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Article
Open AccessHuman monocytes and macrophages differ in their mechanisms of adaptation to hypoxia
Inflammatory arthritis is a progressive disease with chronic inflammation of joints, which is mainly characterized by the infiltration of immune cells and synovial hyperproliferation. Monocytes migrate towards...
