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  1. Article

    Open Access

    MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during pathogenesis of osteoarthritis

    Even though osteoarthritis (OA) is the most common musculoskeletal dysfunction, there are no effective pharmacological treatments to treat OA due to lack of understanding in OA pathology. To better understand ...

    **soo Song, Dongkyun Kim, Chang Hoon Lee, Myeung Su Lee… in Journal of Biomedical Science (2013)

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    Article

    Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

    In two studies from teams led by Hiroshi Kawaguchi and Jang-Soo Chun, a role for HIF-2α in osteoarthritis has been uncovered. Along with identifying the molecular mechanism, the teams found that HIF-2α express...

    Siyoung Yang, Jonghwan Kim, Je-Hwang Ryu, Hwanhee Oh, Churl-Hong Chun… in Nature Medicine (2010)