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Open AccessEIF4A3-induced Circ_0001187 facilitates AML suppression through promoting ubiquitin-proteasomal degradation of METTL3 and decreasing m6A modification level mediated by miR-499a-5p/RNF113A pathway
Aberrant expression of circRNAs has been proven to play a crucial role in the progression of acute myeloid leukemia (AML); however, its regulatory mechanism remains unclear. Herein, we identified a novel circR...
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Article
Open AccessLkb1 aggravates diffuse large B-cell lymphoma by promoting the function of Treg cells and immune escape
Regulatory T cells (Tregs) induce immune responses and may contribute to immune escape in tumors. Accumulation of Tregs in tumors represents a critical barrier to anti-tumor immunity and immunotherapy. However...
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Article
Open AccessRole of CDH23 as a prognostic biomarker and its relationship with immune infiltration in acute myeloid leukemia
Cadherin-23 (CDH23) plays an important role in intercellular adhesion and is involved in the progression of several types of cancer. However, the biological functions and effect of CDH23 expression on the prog...
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Article
Open AccessEarly BCR-ABL1 decline in imatinib-treated patients with chronic myeloid leukemia: results from a multicenter study of the Chinese CML alliance
An early molecular response is spectacularly predictive of outcome in chronic myeloid leukemia (CML) and early response landmarks may identify the high-risk patients likely to be benefit from an early therapy ...
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Article
Response gene to complement 32 (RGC-32) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4
Response gene to complement 32 (RGC-32) is a cell cycle regulator involved in the proliferation, differentiation and migration of cells and has also been implicated in angiogenesis. Here we show that RGC-32 ex...
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Article
Open AccessWnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation
We previously demonstrated that 6-benzylthioinosine (6-BT) could induce the differentiation of a subset of acute myeloid leukemia (AML) cell lines and primary AML cells regardless of their cytogenetics. In thi...
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Article
Open AccessThe emerging roles of Notch signaling in leukemia and stem cells
The Notch signaling pathway plays a critical role in maintaining the balance between cell proliferation, differentiation and apoptosis, and is a highly conserved signaling pathway that regulates normal develop...
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Article
Solution-processed bulk heterojunction solar cells based on interpenetrating CdS nanowires and carbon nanotubes
Incorporation of a bulk heterojunction is an effective strategy to enhance charge separation and carrier transport in solar cells, and has been adopted in polymeric and colloidal nanoparticle solar cells to im...
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Article
Photocatalytic, recyclable CdS nanoparticle-carbon nanotube hybrid sponges
Semiconducting nanoparticles with lower bandgap (e.g., CdS) are alternative photocatalysts to TiO2, since they have a potentially wider range light of absorption and improved catalytic efficiency. However, the...
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Article
CuI-Si heterojunction solar cells with carbon nanotube films as flexible top-contact electrodes
We report the fabrication of CuI-Si heterojunction solar cells with carbon nanotubes (CNTs) as a transparent electrode. A flexible CNT network was transferred onto the top of a polycrystalline CuI layer, makin...
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Article
Graphene-CdSe nanobelt solar cells with tunable configurations
We have combined two planar nanostructures, graphene and CdSe nanobelts, to construct Schottky junction solar cells with open-circuit voltages of about 0.5 V and cell efficiencies on the order of 0.1%. By cove...