-
Article
Open AccessMedium-cumulative dose of cytarabine in consolidation therapy shows the greatest benefit in AML patients
High-dose cytarabine (HDAC) is commonly used for consolidation therapy in young acute myeloid leukemia (AML) patients, but the dosage of cytarabine is still controversial in the clinic due to its obvious post-...
-
Chapter and Conference Paper
Design and Verification of Satellite Propulsion Layout with Force Couple for AC and Multi-thrust Options for OC
Considering the requirements of traditional thruster layout, the characteristics of missions and working loads of the satellites, a thruster layout method for attitude controlling (AC) with force couple and or...
-
Article
Open AccessPredictive model for epileptogenic tubers from all tubers in patients with tuberous sclerosis complex based on 18F-FDG PET: an 8-year single-centre study
More than half of patients with tuberous sclerosis complex (TSC) suffer from drug-resistant epilepsy (DRE), and resection surgery is the most effective way to control intractable epilepsy. Precise preoperative...
-
Article
Recompensation in treatment-naïve HBV-related decompensated cirrhosis: a 5-year multi-center observational study comparing patients with ascites and bleeding
Recompensation between patients with ascites and bleeding was unknown in treatment-naïve HBV-related decompensated cirrhosis.
-
Article
Association of nonmalignant portal vein thrombosis and clinical outcomes in patients with cirrhosis and acute variceal bleeding: a multicenter observational study
Baveno VII workshop recommends management of acute variceal bleeding (AVB) in cirrhotic patients with nonmalignant portal vein thrombosis (PVT) should be performed according to the guidelines for patients with...
-
Article
Open AccessAbsence seizures in lesion-related epilepsy
In the new International League Against Epilepsy (ILAE) classification of seizure types, generalized seizures such as absence seizures (ASs) may originate from a focal point and rapidly spread to the bilateral...
-
Article
Open AccessIndividualized portal pressure gradient threshold based on liver function categories in preventing rebleeding after TIPS
The evidence in Portal pressure gradient (PPG) < 12 mmHg after transjugular intrahepatic portosystemic shunt (TIPS) for preventing rebleeding mostly comes from observations in uncovered stents era. Moreover, a...
-
Article
Optimal time point of response assessment for predicting survival is associated with tumor burden in hepatocellular carcinoma receiving repeated transarterial chemoembolization
Objective response rate (ORR) under mRECIST criteria after transarterial chemoembolization (TACE) is a well-perceived surrogate endpoint of overall survival (OS). However, its optimal time point remains contro...
-
Article
Design, synthesis and characterization of SEBS anion exchange membranes with ultrahigh dimensional stability
Poly(styrene-b-(ethylene-co-butylene)-b-styrene) copolymer (SEBS) has been widely used for anion exchange membranes (AEMs). However, it is still challenging to improve the dimensional stability of SEBS based A...
-
Article
Open AccessPotential prognosis index for m6A-related mRNA in cholangiocarcinoma
Cholangiocarcinoma (CHOL) is a malignant tumor that originates in the extrahepatic bile duct and can extend from the hilar region to the lower end of the common bile duct. The prognosis of CHOL patients is par...
-
Article
Open AccessBrain-wide projection reconstruction of single functionally defined neurons
Reconstructing axonal projections of single neurons at the whole-brain level is currently a converging goal of the neuroscience community that is fundamental for understanding the logic of information flow in ...
-
Article
Open AccessTranscriptome analysis reveals the mechanism of internode development affecting maize stalk strength
The stalk rind is one of the important factors affecting maize stalk strength that is closely related to stalk lodging. However, the mechanism of rind development in maize is still largely unknown.
-
Article
Novel insights of maize structural feature in China
Maize (Zea mays L.) is a globally important crop species that feeds much of the world’s population and possesses morphology and phenotypic diversity that allow it to be manipulated to produce more productive vari...
-
Article
Open AccessA blended intervention to promote physical activity, health and work productivity among office employees using intervention map**: a study protocol for a cluster-randomized controlled trial
Regular participation in moderate-to-vigorous physical activity (MVPA) is related to decreased risk of morbidity and mortality. Among working populations, lack of MVPA may also be a risk factor for absenteeism...
-
Article
Open AccessDecreased expression of Rev-Erbα in the epileptic foci of temporal lobe epilepsy and activation of Rev-Erbα have anti-inflammatory and neuroprotective effects in the pilocarpine model
A hallmark of temporal lobe epilepsy (TLE) is brain inflammation accompanied by neuronal demise. Accumulating evidence demonstrates that Rev-Erbα is involved in regulating neuroinflammation and determining the...
-
Article
Open AccessRASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway
Recent studies have confirmed that RASAL1 has an antitumor effect in many cancers, but its functional role and the molecular mechanism underlying in colon cancer has not been investigated.
-
Article
Open AccessTranscriptome analysis reveals the mechanism by which spraying diethyl aminoethyl hexanoate after anthesis regulates wheat grain filling
Diethyl aminoethyl hexanoate (DA-6), a plant growth regulator, has many beneficial effects on agricultural production. DA-6 has been applied to many plant species, but the molecular mechanism by which spraying...
-
Article
Hormone and RNA-seq analyses reveal the mechanisms underlying differences in seed vigour at different maize ear positions
ABA/GA4 ratio, stress resistance, carbon and nitrogen metabolism, and chromatin structure play important roles in vigour differences of seeds located at different maize ear positions.
-
Article
Comparative Proteomics Reveals the Mechanisms Underlying Variations in Seed Vigor Based on Maize (Zea mays L.) Ear Positions
Seed vigor is influenced by seed position in plant. However, current understanding of its underlying mechanism is limited. In this study, we used isobaric tags for relative and absolute quantitation technique ...
-
Article
Angiotensin II receptor blockers for the treatment of portal hypertension in patients with liver cirrhosis: a systematic review and meta-analysis of randomized controlled trials
Randomized controlled trials (RCTs) showed inconsistent results regarding the efficacy of angiotensin II receptor blockers (ARBs) on portal pressure as indicated by hepatic venous pressure gradient (HVPG).
