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  1. No Access

    Article

    Regulated Cell Death of Retinal Ganglion Cells in Glaucoma: Molecular Insights and Therapeutic Potentials

    Glaucoma is a group of diseases characterized by the degeneration of retinal ganglion cells (RGCs) and progressive, irreversible vision loss. High intraocular pressure (IOP) heightens the likelihood of glaucom...

    Wen-juan Zhao, Chun-ling Fan, **-min Hu… in Cellular and Molecular Neurobiology (2023)

  2. Article

    Open Access

    A novel method to identify the flow pattern of oil–water two-phase flow

    This paper presents a novel method combining extreme learning machine (ELM) and multiple empirical mode decomposition (MEMD) to identify flow patterns of oil–water two-phase flow. The proposed method can recog...

    Zhong-Cheng Li, Chun-Ling Fan in Journal of Petroleum Exploration and Production Technology (2020)

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  3. No Access

    Article

    Microstructure, wear and corrosion performance of plasma electrolytic oxidation coatings formed on D16T Al alloy

    The plasma electrolytic oxidation (PEO) coatings were produced on D16T Al alloy in the aluminate and silicate electrolyte with and without graphene. The phase composition, microstructure and elemental distribu...

    Wan-Ying Liu, Ying Liu, Carsten Blawert, Mikhail-L. Zheludkevich… in Rare Metals (2020)

  4. Article

    Open Access

    Timosaponin-BII inhibits the up-regulation of BACE1 induced by Ferric Chloride in rat retina

    Our previous studies indicated that oxidative stress up-regulated the expression of β-amyloid precursor protein cleavage enzyme-1 (BACE1) in rat retina. Pharmacological reports have shown Timosaponin-BII, a pu...

    Ju-Fang Huang, Lei Shang, Pei Liu… in BMC Complementary and Alternative Medicine (2012)

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  5. Article

    Open Access

    Chronic lead exposure reduces doublecortin-expressing immature neurons in young adult guinea pig cerebral cortex

    Chronic lead (Pb) poisoning remains an environmental risk especially for the pediatric population, and it may affect brain development. Immature neurons expressing doublecortin (DCX+) exist around cortical lay...

    JuFang Huang, Kai Huang, Lei Shang, Hui Wang, Mengqi Zhang… in BMC Neuroscience (2012)

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  6. No Access

    Article

    Expression of human papillomavirus in mammary carcinoma and its possible mechanism in carcinogenesis

    To explore the role of Human papillomavirus (HPV) in mammary carcinogenesis, the expression of the HPV-16, iNOS, P53 and hTERT proteins in breast carcinomas and their relationships were investigated. 52 sample...

    Chun-ling Fan, **g-hua Zhou, Cheng-yi Hu in Virologica Sinica (2008)

  7. Article

    Angiotensin II-Stimulated Collagen Synthesis in Aortic Adventitial Fibroblasts Is Mediated by Connective Tissue Growth Factor

    Angiotensin II (Ang II), a potent mediator of vascular remodeling, can stimulate the synthesis of extracellular matrix in vascular cells. Recent studies indicate that connective tissue growth factor (CTGF) is ...

    Zai-qian Che, **-** Gao, Wei-li Shen, Chun-ling Fan… in Hypertension Research (2008)

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  8. Article

    Circulating Endothelial Progenitor Cells, C-Reactive Protein and Severity of Coronary Stenosis in Chinese Patients with Coronary Artery Disease

    We sought to investigate whether numbers and activity of circulating endothelial progenitor cells (EPCs) correlate with severity of coronary stenosis as well as cardiovascular risk factors in patients with sta...

    Hai-Ya Wang, **-** Gao, Kai-Da Ji, Wei-Feng Shen, Chun-Ling Fan… in Hypertension Research (2007)

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  9. Article

    Therapeutic neovascularization by autologous transplantation with expanded endothelial progenitor cells from peripheral blood into ischemic hind limbs

    To investigate the hypothesis that transplantation with expanded autologous endothelial progenitor cells (EPC) could enhance neovascularization.

    Chun-ling Fan, **-** Gao, Zai-qian Che, Jian-jun Liu… in Acta Pharmacologica Sinica (2005)

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