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  1. Article

    Open Access

    Canagliflozin alleviates pulmonary hypertension by activating PPARγ and inhibiting its S225 phosphorylation

    Pulmonary hypertension (PH) is a progressive fatal disease with no cure. Canagliflozin (CANA), a novel medication for diabetes, has been found to have remarkable cardiovascular benefits. However, few studies h...

    **u-chun Li, **a-yan Zhu, Yang-yue Wang, Shuo-lan Tong in Acta Pharmacologica Sinica (2024)

  2. Article

    Open Access

    Total laparoscopic partial hepatectomy versus open partial hepatectomy for primary left-sided hepatolithiasis: study protocol for a randomized controlled trial

    The advantages of laparoscopic left-sided hepatectomy (LLH) for treating hepatolithiasis in terms of the time to postoperative length of hospital stay (LOS), morbidity, long-term abdominal wall hernias, hospit...

    Shu-bo Pan, Chun-li Wu, Da-chen Zhou, Qi-ru **ong, ** Geng, Hui Hou in Trials (2024)

  3. No Access

    Article

    Simultaneously enhanced interfacial shear strength and tensile strength of heterocyclic aramid fiber by graphene oxide

    Heterocyclic aramid fibers, a typical kind of high-performance fibers, have been widely used in aerospace and protection fields because of their excellent mechanical properties. However, the application of het...

    Ziyi Zhang, **angzheng Jia, Chun Li, Lanying Li, Yeye Wen, Zhenfei Gao in Nano Research (2023)

  4. Article

    Open Access

    Association of dietary inflammatory index with helicobacter pylori infection and mortality among US population

    Limited research has been conducted on the potential relationship between the dietary inflammation index (DII) and mortality, particularly in individuals with Helicobacter pylori (H. pylori) infection. This st...

    Yu-Jun **ong, Lei-Lei Du, Yun-Lian Diao, Jun Wen in Journal of Translational Medicine (2023)

  5. No Access

    Article

    Construction of charge transfer chain in Bi12TiO20-Bi4Ti3O12/α-Bi2O3 composites to accelerate photogenerated charge separation

    Photogenerated charge separation and transfer is one of the bottleneck steps in photocatalysis, and efficient charge separation strategies are strongly desired. Here, mimicking the electron transport chain in ...

    **cheng Yin, Xuebing Chen, Guanna Li, Dongxu Liu, Chun Li, Rengui Li in Nano Research (2023)

  6. No Access

    Article

    An on-Si directional second harmonic generation amplifier for MoS2/WS2 heterostructure

    Transition metal dichalcogenides (TMD) heterostructure is widely applied for second harmonic generation (SHG) and holds great promises for laser source, nonlinear switch, and optical logic gate. However, for a...

    Jiaxing Du, Jianwei Shi, Chun Li, Qiuyu Shang, **nfeng Liu, Yuan Huang in Nano Research (2023)

  7. Article

    Open Access

    Effect of positive event recording based on positive psychology on healthy behaviors and readmission rate of patients after PCI: a study protocol for a prospective, randomized controlled trial

    Unhealthy behaviors of coronary heart disease (CHD) patients are closely related to the occurrence of major heart events, which increases the readmission rate and brings a heavy economic burden to families and...

    Yao-Yao Hu, **n Jiang, Fang-Ying Mao, **g Zhang, Lin Liu, Jie Gu, Qing Wu in Trials (2022)

  8. No Access

    Article

    Utility of cell-free DNA from bronchial washing fluid in diagnosis and genomic determination for radiology-suspected pulmonary nodules

    Bronchial washing fluid (BWF) is a less-invasive specimen. Due to the limited sensitivity of BWF cellular component diagnosis, the aim of this study was to explore the potential role of BWF supernatant as a so...

    **nyu Zhang, Zhuo Yu, Ya** Xu, Yencheng Chao, Qin Hu in British Journal of Cancer (2022)

  9. Article

    Open Access

    Effects of robotic priming of bilateral arm training, mirror therapy, and impairment-oriented training on sensorimotor and daily functions in patients with chronic stroke: study protocol of a single-blind, randomized controlled trial

    Combining robotic therapy (RT) with task-oriented therapy is an emerging strategy to facilitate motor relearning in stroke rehabilitation. This study protocol will compare novel rehabilitation regimens that us...

    Yi-chen Lee, Yi-chun Li, Keh-chung Lin, Grace Yao, Ya-ju Chang, Ya-yun Lee in Trials (2022)

  10. No Access

    Article

    Time-resolved Fluorescence Immunoassay (TRFIA) for the Simultaneous Detection of MMP-9 and Lp-PLA2 in Serum

    Currently, atherosclerosis accounts for the majority of cardiovascular morbidity and mortality worldwide, and predicting the stability of atherosclerotic plaque is the main method to prevent atherosclerotic de...

    Hong-yan Ma, Qian Mao, Yan-bin Zhu, Chun-li Cong, Shi-yu Zheng in Journal of Fluorescence (2021)

  11. No Access

    Article

    Strong exciton-photon interaction and lasing of two-dimensional transition metal dichalcogenide semiconductors

    Two-dimensional (2D) transition metal dichalcogenide (TMDC) semiconductors not only hold great promises for the development of ultra-thin optoelectronic devices with low-energy consumption, but also provide id...

    Liyun Zhao, Qiuyu Shang, Meili Li, Yin Liang, Chun Li, Qing Zhang in Nano Research (2021)

  12. Article

    Author Correction: Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Chuanhui Han, Zhida Liu, Yunjia Zhang, Aijun Shen, Chunbo Dong in Nature Immunology (2020)

  13. Article

    Open Access

    Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation

    Palladin is a ubiquitous phosphoprotein expressed in vertebrate cells that works as a scaffolding protein. Several isoforms deriving from alternative splicing are originated from the palladin gene and involved...

    Boimpoundi Eunice Flavie Ouali, Tzu-Yu Liu, Chun-Yen Lu in BMC Research Notes (2020)

  14. No Access

    Article

    Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling

    High-dose radiation activates caspases in tumor cells to produce abundant DNA fragments for DNA sensing in antigen-presenting cells, but the intrinsic DNA sensing in tumor cells after radiation is rather limit...

    Chuanhui Han, Zhida Liu, Yunjia Zhang, Aijun Shen, Chunbo Dong in Nature Immunology (2020)

  15. No Access

    Article

    Synthesis of Novel Chalcone-Based L-Homoserine Lactones and Their Quorum Sensing Inhibitory Activity Evaluation

    Two novel series of chalcone-based homoserine lactones were synthesized and their quorum sensing (QS) inhibitory activity was evaluated against Pseudomonas aeruginosa in vitro. Furthermore these compounds’ capaci...

    Chunying Luo, Pan Li, Haoyue Liu, Pengxia Feng in Russian Journal of Bioorganic Chemistry (2020)

  16. No Access

    Article

    Wafer-scale synthesis of monolayer WS2 for high-performance flexible photodetectors by enhanced chemical vapor deposition

    Two-dimensional (2D) nanomaterials have recently attracted considerable attention due to their promising applications in next-generation electronics and optoelectronics. In particular, the large-scale synthesi...

    Changyong Lan, Ziyao Zhou, Zhifei Zhou, Chun Li, Lei Shu, Lifan Shen in Nano Research (2018)

  17. Article

    Open Access

    S-nitrosylation of transglutaminase 2 impairs fatty acid-stimulated contraction in hypertensive cardiomyocytes

    The myocardium in hypertensive heart exhibits decreased fatty acid utilization and contractile dysfunction, leading to cardiac failure. However, the causal relationship between metabolic remodeling and cardiom...

    Eui Man Jeong, Chun Zi **, Ji Hyun Jang, Zai Hao Zhao in Experimental & Molecular Medicine (2018)

  18. No Access

    Article

    Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus

    Low-dose IL-2 treatment alters the abundance of regulatory T cells, IL-17-producing T cells and follicular helper T cells, but not of T helper type 1 and 2 cells, in patients with SLE.

    **g He, **a Zhang, Yunbo Wei, **aolin Sun, Ya** Chen, Jun Deng in Nature Medicine (2016)

  19. Article

    Open Access

    Anticancer drug sensitivity prediction in cell lines from baseline gene expression through recursive feature selection

    An enduring challenge in personalized medicine is to select right drug for individual patients. Testing drugs on patients in large clinical trials is one way to assess their efficacy and toxicity, but it is im...

    Zuoli Dong, Naiqian Zhang, Chun Li, Haiyun Wang, Yun Fang, Jun Wang in BMC Cancer (2015)

  20. No Access

    Article

    Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1

    Qiuyin Cai and colleagues report a genome-wide association analysis for breast cancer in 22,780 cases and 24,181 controls from 14 studies as part of the Asia Breast Cancer Consortium. They identify three loci ...

    Qiuyin Cai, Ben Zhang, Hyuna Sung, Siew-Kee Low, Sun-Seog Kweon, Wei Lu in Nature Genetics (2014)

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