39 Result(s)
within
Chun**ao Wei
Life Sciences
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Article
Open AccessAltered microbiome of serum exosomes in patients with acute and chronic cholecystitis
This study aimed to investigate the differences in the microbiota composition of serum exosomes from patients with acute and chronic cholecystitis.
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Open AccessA novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens
The plasma membrane is enriched for receptors and signaling proteins that are accessible from the extracellular space for pharmacological intervention. Here we conducted a series of CRISPR screens using human ...
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Article
Open AccessLow-glucose culture environment can enhance the wound healing capability of diabetic adipose-derived stem cells
Application of autologous adipose-derived stem cells (ASC) for diabetic chronic wounds has become an emerging treatment option. However, ASCs from diabetic individuals showed impaired cell function and subopti...
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Open AccessSpatiotemporal control of genome engineering in cone photoreceptors
Cones are essential for color recognition, high resolution, and central vision; therefore cone death causes blindness. Understanding the pathophysiology of each cell type in the retina is key to develo** the...
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Open AccessGenome-wide identification and characterization of polycomb repressive complex 2 core components in upland cotton (Gossypium hirsutum L.)
The evolutionarily conserved Polycomb Repressive Complex 2 (PRC2) plays a vital role in epigenetic gene repression by depositing tri-methylation on lysine residue K27 of histone H3 (H3K27me3) at the target loc...
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Open AccessBMSCs improve TNBS-induced colitis in rats by inducing Treg differentiation by expressing PD-L1
Bone marrow-derived mesenchymal stem cells (BMSCs) show promise in treating inflammatory bowel disease. We tested if BMSCs improve Trinitro-benzene-sulfonic acid (TNBS)-induced colitis by inducing Treg differe...
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Open AccessEnsemble learning for predicting ex vivo human placental barrier permeability
The placental barrier protects the fetus from exposure to some toxicants and is vital for drug development and risk assessment of environmental chemicals. However, in vivo experiments for assessing the placent...
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Open AccessThe speckle-type POZ protein (SPOP) inhibits breast cancer malignancy by destabilizing TWIST1
Epithelial-mesenchymal transition (EMT) inducing transcription factor TWIST1 plays a vital role in cancer metastasis. How the tumor-suppressive E3 ligase, speckle-type POZ protein (SPOP), regulates TWIST1 in b...
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Open AccessAFD-Net: Apple Foliar Disease multi classification using deep learning on plant pathology dataset
Plant diseases significantly affect the crop, so their identification is very important. Correct identification of these diseases is crucial for establishing a good disease control strategy to avoid time and f...
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Open AccessGenome-wide identification, phylogeny and expression analysis of the SPL gene family and its important role in salt stress in Medicago sativa L.
SQUAMOSA promoter-binding protein-like (SPL) transcription factors are widely present in plants and are involved in signal transduction, the stress response and development. The SPL gene family has been character...
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Open AccessUsing machine learning to determine the correlation between physiological and environmental parameters and the induction of acute mountain sickness
Recent studies on acute mountain sickness (AMS) have used fixed-location and fixed-time measurements of environmental and physiological variable to determine the influence of AMS-associated factors in the huma...
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Open AccessAcute cannabinoids impair association learning via selectively enhancing synaptic transmission in striatonigral neurons
Cannabinoids and their derivatives attract strong interest due to the tremendous potential of their psychoactive effects for treating psychiatric disorders and symptoms. However, their clinical application is ...
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Open AccessTwo genomic regions of a sodium azide induced rice mutant confer broad-spectrum and durable resistance to blast disease
Rice blast, one of the most destructive epidemic diseases, annually causes severe losses in grain yield worldwide. To manage blast disease, breeding resistant varieties is considered a more economic and enviro...
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Open AccessLactobacillus plantarum surface-displayed ASFV (p54) with porcine IL-21 generally stimulates protective immune responses in mice
African classical swine fever virus (ASFV) has spread seriously around the world and has dealt with a heavy blow to the pig breeding industry due to the lack of vaccines. In this study, we produced recombinant La...
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Open AccessWDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
WDR62 is a scaffold protein involved in centriole duplication and spindle assembly during mitosis. Mutations in WDR62 can cause primary microcephaly and premature ovarian insufficiency. We have generated a genetr...
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Expressions and significances of the angiotensin-converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-19
The ACE2 gene is a receptor of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) for COVID-19 (coronavirus disease 2019). To analyze the expression profiles and clinical significances for this gene in ...
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Open AccessA new genus and species of foliicolous lichen in a new family of Strigulales (Ascomycota: Dothideomycetes) reveals remarkable class-level homoplasy
Phylogenetic analysis of some foliicolous lichens collected in Hainan Province, China, revealed a new lineage morphologically similar to Porina but phylogenetically related to Strigulaceae (Dothideomycetes), diff...
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Article
Correction to: Characterization and molecular cloning of novel isoforms of human spermatogenesis associated gene SPATA3
Unfortunately, as for the second institute name of first author Baixu Zhou, “Department of Gynecology and Obstetrics, Guangzhou Women and Children’s Hospital, Guangzhou, Guangdong, China”, should be “Departmen...
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Immune responses induced by recombinant Lactobacillus plantarum expressing the spike protein derived from transmissible gastroenteritis virus in piglets
Transmissible gastroenteritis coronavirus (TGEV) is one of the most severe threats to the swine industry. In this study, we constructed a suite of recombinant Lactobacillus plantarum with surface displaying the s...
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Immune response characterization of mice immunized with Lactobacillus plantarum expressing spike antigen of transmissible gastroenteritis virus
The highly infectious porcine transmissible gastroenteritis virus (TGEV), which belongs to the coronaviruses (CoVs), causes diarrhea and high mortality rates in piglets, resulting in severe economic losses in ...
