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    Article

    POM-1 inhibits P2 receptors and exhibits anti-inflammatory effects in macrophages

    Extracellular nucleotides can modulate the immunological response by activating purinergic receptors (P2Rs) on the cell surface of macrophages, dendritic, and other immune cells. In particular, the activation ...

    Gabriela Pimenta-dos-Reis, Eduardo José Lopes Torres in Purinergic Signalling (2017)

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    Open Access

    Correction: Corrigendum: Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota

    Nature Communications 6: Article number:7489 (2015); Published: 23 June 2015; Updated: 11 July 2017 The image in Fig. 1e of this Article showing the ‘HFD+8%’ group was inadvertently duplicated from the ‘Chow+8...

    Chih-Jung Chang, Chuan-Sheng Lin, Chia-Chen Lu, Jan Martel in Nature Communications (2017)

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    Article

    Anti-obesogenic and antidiabetic effects of plants and mushrooms

  4. The prevalence of obesity is increasing worldwide as a result of high-calorie diets and sedentary lifestyles

  5. ...
  6. Jan Martel, David M. Ojcius, Chih-Jung Chang in Nature Reviews Endocrinology (2017)

  7. Article

    Open Access

    An iron detection system determines bacterial swarming initiation and biofilm formation

    Iron availability affects swarming and biofilm formation in various bacterial species. However, how bacteria sense iron and coordinate swarming and biofilm formation remains unclear. Using Serratia marcescens as ...

    Chuan-Sheng Lin, Yu-Huan Tsai, Chih-Jung Chang, Shun-Fu Tseng in Scientific Reports (2016)

  8. Article

    Open Access

    Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota

    Obesity is associated with low-grade chronic inflammation and intestinal dysbiosis. Ganoderma lucidum is a medicinal mushroom used in traditional Chinese medicine with putative anti-diabetic effects. Here, we sho...

    Chih-Jung Chang, Chuan-Sheng Lin, Chia-Chen Lu, Jan Martel in Nature Communications (2015)

  9. Article

    Open Access

    Rapid identification of Mycobacterium tuberculosis infection by a new array format-based surface plasmon resonance method

    Tubercle bacillus [TB] is one of the most important chronic infectious diseases that cause millions of deaths annually. While conventional smear microscopy and culture methods are widely used for diagnosis of ...

    Shang-Chen Hsieh, Chia-Chen Chang, Chia-Chen Lu in Nanoscale Research Letters (2012)