1,041 Result(s)
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Article
Full-length GSDME mediates pyroptosis independent from cleavage
Gasdermin (GSDM) family proteins, known as the executors of pyroptosis, undergo protease-mediated cleavage before inducing pyroptosis. We here discovered a form of pyroptosis mediated by full-length (FL) GSDME...
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Open AccessCorrection: ABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies
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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster proteins as a unique copper-dependent form of regulated cell dea...
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Open AccessSystematic Mendelian Randomization Exploring Druggable Genes for Hemorrhagic Strokes
Patients with hemorrhagic stroke have high rates of morbidity and mortality, and drugs for prevention are very limited. Mendelian randomization (MR) analysis can increase the success rate of drug development b...
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Open AccessHighly extensile approach for comminuted ulna coronoid process fractures with mini-plate fixation: a case series of 31 patients
For the treatment of coronoid process fractures, medial, lateral, anterior, anteromedial, and posterior approaches have been increasingly reported; however, there is no general consensus on the method of fixat...
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The impact of photobiomodulation on sleep and life quality in hemodialysis patients: A randomized controlled trial
The quality of life (QoL) and sleep quality are closely linked to the physical and psychological health of end-stage renal disease (ESRD) patients, especially those underwent hemodialysis (HD) therapy. This st...
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Article
Integrating organoids and organ-on-a-chip devices
Organoids and organs-on-chips are two rapidly emerging 3D cell culture techniques that aim to bridge the gap between in vitro 2D cultures and animal models to enable clinically relevant drug discovery and mode...
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Open AccessIntravitreal ranibizumab injection is associated with an increased risk of chronic kidney disease: a population-based study in Taiwan
Systemic vascular endothelial growth factor (VEGF) blockade has been the top adjunctive chemotherapy since 1990. Anti-VEGF therapy has also been associated with worsened renal function in some patients. Howeve...
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The Solar Origin of an Intense Geomagnetic Storm on 1 December 2023: Successive Slip** and Eruption of Multiple Magnetic Flux Ropes
The solar eruption that occurred on 28 November 2023 (SOL2023-11-28) triggered an intense geomagnetic storm on 1 December 2023. The associated terrestrial auroras manifested at the most southern latitudes in t...
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DeepPollenCount: a swin-transformer-YOLOv5-based deep learning method for pollen counting in various plant species
Accurate identification and quantification of pollens (e.g., pollen of a flower, airborne pollens) is essential to understand plant pollination and reproductive biology, pollen aerobiology, and plant–insect in...
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Open AccessDiagnosis and treatment status of inoperable locally advanced breast cancer and the application value of inorganic nanomaterials
Locally advanced breast cancer (LABC) is a heterogeneous group of breast cancer that accounts for 10–30% of breast cancer cases. Despite the ongoing development of current treatment methods, LABC remains a sev...
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Open AccessGeometric data analysis-based machine learning for two-dimensional perovskite design
With extraordinarily high efficiency, low cost, and excellent stability, 2D perovskite has demonstrated a great potential to revolutionize photovoltaics technology. However, inefficient material structure repr...
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Open AccessCXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity
The interaction between glioblastoma cells and glioblastoma-associated macrophages (GAMs) influences the immunosuppressive tumor microenvironment, leading to ineffective immunotherapies. We hypothesized that d...
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Author Correction: RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis
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Open AccessPPIH acts as a potential predictive biomarker for patients with common solid tumors
Our previous studies have indicated that mRNA and protein levels of PPIH are significantly upregulated in Hepatocellular Carcinoma (LIHC) and could act as predictive biomarkers for patients with LIHC. Nonetheless...
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Open AccessSIRPG expression positively associates with an inflamed tumor microenvironment and response to PD-1 blockade
This study aimed to investigate the relationship between signal regulatory protein gamma (SIRPG) and tumor immune microenvironment phenotypes or T cell mediated-adaptive antitumor immunity, and its predictive ...
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Open AccessAssociation between statin therapy and long-term clinical outcomes in patients with stable coronary disease undergoing percutaneous coronary intervention
This longitudinal cohort study examined the long-term effect of statin therapy on clinical outcomes in patients undergoing percutaneous coronary intervention (PCI). A total of 1760 patients with stable coronar...
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Open AccessResource theory of imaginarity in distributed scenarios
The resource theory of imaginarity studies the operational value of imaginary parts in quantum states, operations, and measurements. Here we introduce and study the distillation and conversion of imaginarity i...
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Open AccessChineseEEG: A Chinese Linguistic Corpora EEG Dataset for Semantic Alignment and Neural Decoding
An Electroencephalography (EEG) dataset utilizing rich text stimuli can advance the understanding of how the brain encodes semantic information and contribute to semantic decoding in brain-computer interface (...
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Article
Open AccessABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies
Numerous studies have been conducted to investigate the relationship between ABO and Rhesus (Rh) blood groups and various health outcomes. However, a comprehensive evaluation of the robustness of these associa...