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    Article

    Tumor Deposit Is an Independent Factor Predicting Early Recurrence and Poor Prognosis in Gastric Cancer

    Accurate prognostic estimation is crucial; however, the prognostic value of tumor deposits in gastric cancer remains controversial. This study aimed to investigate their prognostic significance.

    Kaoru Fujikawa, Takeshi Omori, Naoki Shinno in Journal of Gastrointestinal Surgery (2023)

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    Article

    Laparoscopic Proximal Gastrectomy with Novel Valvuloplastic Esophagogastrostomy vs. Laparoscopic Total Gastrectomy for Stage I Gastric Cancer: a Propensity Score Matching Analysis

    Laparoscopic total gastrectomy for early proximal gastric cancer is widely performed. Recently, the number of laparoscopic proximal gastrectomies performed, a surgery limited to early proximal gastric cancer, ...

    Masaaki Yamamoto, Takeshi Omori, Naoki Shinno in Journal of Gastrointestinal Surgery (2022)

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    Article

    Comparison of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer: a propensity score-matched analysis

    The benefits of robotic gastrectomy (RG) over laparoscopic gastrectomy (LG) remain controversial. This single-center, propensity score-matched study aimed to compare the outcomes of RG with those of LG for tre...

    Takeshi Omori, Kazuyoshi Yamamoto, Hisashi Hara, Naoki Shinno in Surgical Endoscopy (2022)

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    Article

    Fecal Stream Diversion Changes Intestinal Environment, Modulates Mucosal Barrier, and Attenuates Inflammatory Cells in Crohn’s Disease

    The intestinal environment plays important roles in mucosal barrier homeostasis and intestinal inflammation, as clarified in studies using experimental animals but not in humans.

    Yoshifumi Watanabe, Tsunekazu Mizushima, Ryu Okumura in Digestive Diseases and Sciences (2022)

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    Article

    Clinical importance of carcinoembryonic antigen messenger RNA level in peritoneal lavage fluids measured by transcription-reverse transcription concerted reaction for advanced gastric cancer in laparoscopic surgery

    Transcription-reverse transcription concerted reaction (TRC) is recognized as a useful method for detecting free cancer cells in the peritoneal cavity and predicting peritoneal recurrence in patients with gast...

    Kohei Fujita, Takeshi Omori, Hisashi Hara, Naoki Shinno in Surgical Endoscopy (2022)

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    Article

    Pre-emptive oral clarithromycin reduces the skin toxicity of panitumumab treatment for metastatic colorectal cancer

    Chemotherapy with panitumumab is expected to be well tolerated and improve survival in patients with metastatic colorectal cancer (mCRC). However, skin toxicities are its most common adverse events. The aim of...

    Ken Nakata, Takamichi Komori, Kazuhiro Saso in International Journal of Colorectal Disease (2021)

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    Article

    Cumulative Inflammation Could Be a Risk Factor for Intestinal Failure in Crohn’s Disease

    Intestinal failure is the most critical complication of Crohn’s disease. Intestinal failure requires home parenteral nutrition, which worsens the quality of life of the patients and sometimes causes life-threa...

    Yoshifumi Watanabe, Norikatsu Miyoshi, Shiki Fu**o in Digestive Diseases and Sciences (2019)

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    Article

    Clinical benefits of single-incision laparoscopic surgery for postoperative delirium in elderly colon cancer patients

    The number of elderly patients with colon cancer is increasing in Japan. Postoperative delirium (POD) is a major complication for elderly patients who undergo surgery, and postoperative pain is a common induce...

    Yujiro Nishizawa, Taishi Hata, Ichiro Takemasa, Makoto Yamasaki in Surgical Endoscopy (2018)

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    Article

    Diverticular colitis with progression to ulcerative colitis after sigmoidectomy

    Diverticular colitis is chronic inflammation of the colon where diverticula are present. The endoscopic and histopathological findings of this disease are sometimes similar to those of ulcerative colitis, and ...

    Atsuyo Ikeda, Tsunekazu Mizushima, Yutaro Egashira in Clinical Journal of Gastroenterology (2018)

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    Article

    Adipose-Derived Stem Cells Ameliorate Experimental Murine Colitis via TSP-1-Dependent Activation of Latent TGF-β

    Adipose tissue-derived stem cells (ASCs) have been investigated as therapeutic tools for a variety of autoimmune diseases, including inflammatory diseases. However, the mechanisms underlying the immunomodulato...

    Hiroshi Takeyama, Tsunekazu Mizushima, Mamoru Uemura in Digestive Diseases and Sciences (2017)

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    Article

    Late toxicity after definitive chemoradiotherapy for esophageal squamous cell carcinoma

    This study was designed to conduct a retrospective analysis of late toxicity following chemoradiotherapy (CRT) for esophageal carcinoma.

    Kazuhiro Nishikawa, Kazuhiro Iwase, Toyokazu Aono, Masaya Nomura in Esophagus (2010)