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  1. Article

    Open Access

    Nucleotide imbalance decouples cell growth from cell proliferation

    Nucleotide metabolism supports RNA synthesis and DNA replication to enable cell growth and division. Nucleotide depletion can inhibit cell growth and proliferation, but how cells sense and respond to changes i...

    Frances F. Diehl, Teemu P. Miettinen, Ryan Elbashir… in Nature Cell Biology (2022)

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  2. No Access

    Article

    Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase

    A bisulfite-free sequencing method yields high-confidence 5hmC profiles in low-input samples.

    Emily K Schutsky, Jamie E DeNizio, Peng Hu, Monica Yun Liu… in Nature Biotechnology (2018)