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    Article

    Systems-level effects of allosteric perturbations to a model molecular switch

    Molecular switch proteins whose cycling between states is controlled by opposing regulators1,2 are central to biological signal transduction. As switch proteins function within highly connected interaction networ...

    Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn Μ. Jang, Yang Zhang… in Nature (2021)

  2. Article

    A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

    A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led ...

    David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier… in Nature (2020)

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