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Article
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
The bite of the Texas coral snake, although not fatal, causes excruciating and long-lasting pain. The toxin involved has now been characterized. The purified active component (MitTx) results from an unusual co...
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Article
Neurotoxic reactive astrocytes are induced by activated microglia
Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease, but their role is poorly understood. Here we show that a subtype of reactive astrocytes, which we termed A1, is indu...