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    Article

    Primary cilia regulate mTORC1 activity and cell size through Lkb1

    The mTOR pathway is a well-known regulator of cell size, and deregulation of mTOR has been observed in cilia-related diseases. Cilia modulate cell size by restricting LKB-1-mediated activation of AMPK to the b...

    Christopher Boehlke, Fruzsina Kotsis, Vishal Patel, Simone Braeg… in Nature Cell Biology (2010)

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    Article

    Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1)

    Primary cilia have been shown to play an important role in embryonic development as well as in postnatal life. Dysfunctional cilia are associated with situs inversus, retinal abnormalities, impaired mucociliary c...

    Fruzsina Kotsis, Roland Nitschke… in Pflügers Archiv - European Journal of Phys… (2007)