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  1. Article

    Open Access

    Biologic Abatement and Capturing Kids’ Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA): study protocol for a randomized pragmatic trial

    The effectiveness of biologic therapies, primarily tumor necrosis factor inhibitors (TNFi), for children with spondyloarthritis (SpA) has made inactive disease a realistic patient outcome. However, biologic th...

    Pamela F. Weiss, Cora E. Sears, Timothy G. Brandon, Christopher B. Forrest in Trials (2023)

  2. Article

    Open Access

    Develo** a framework for the ethical design and conduct of pragmatic trials in healthcare: a mixed methods research protocol

    There is a widely recognized need for more pragmatic trials that evaluate interventions in real-world settings to inform decision-making by patients, providers, and health system leaders. Increasing availabili...

    Monica Taljaard, Charles Weijer, Jeremy M. Grimshaw, Adnan Ali, Jamie C. Brehaut in Trials (2018)