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Protocol
Bayesian Optimization in Drug Discovery
Drug discovery deals with the search for initial hits and their optimization toward a targeted clinical profile. Throughout the discovery pipeline, the candidate profile will evolve, but the optimization will ...
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Article
Open AccessRevisiting fertility regulation and family ties in Tunisia
We revisit fertility regulation in Tunisia by examining the role of the extended family. As marriage is the exclusive acknowledged childbearing context, we examine fertility analysis in Tunisia through the seq...
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Chapter and Conference Paper
Real-Time Renderings of Multidimensional Massive DataCubes on Jupyter Notebook
In this paper we tackle the challenge of visualizing large matrices, also called datacubes, in real time (RT) using Web technologies. The most critical issue is to achieve this for arrays of up to several billion...
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Chapter and Conference Paper
Implicit Curves: From Discrete Extraction to Applied Formalism
This paper addresses the issue of visualizing the right information among large data sets by proposing to represent raw data as a set of mathematically-based implicit curves. Implicit curves are proving to be a p...
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Protocol
Artificial Intelligence, Machine Learning, and Deep Learning in Real-Life Drug Design Cases
The discovery and development of drugs is a long and expensive process with a high attrition rate. Computational drug discovery contributes to ligand discovery and optimization, by using models that describe t...
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Chapter
Emerging Memory Concepts
Recent integration of functional materials in a microelectronic architecture led to new memory concepts presenting disruptive performances as compared to conventional technologies. Beside solutions based on ch...
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Reference Work Entry In depth
Small Bowel Obstruction
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Article
Neosphincter Surgery for Fecal Incontinence: A Critical and Unbiased Review of the Relevant Literature
Up until about 15 years ago the only realistic option for end-stage fecal incontinence was the creation of a permanent stoma. There have since been several developments. Dynamic graciloplasty (DGP) and artific...
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Article
Fecal incontinence: an up-to-date critical overview of surgical treatment options
Surgery is the last resort for patients suffering from severe fecal incontinence. The armamentarium of surgical options for this condition has increased impressively during the last decade. Nevertheless, this ...
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Article
The Valuation of Non-Monetary Consumption in Household Surveys
Many social indicators are based on household consumption information. The valuation of non-monetary operations is crucial for the analysis of consumption surveys in develo** countries because of the importa...
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Article
A Health Production Function for Quasi-Autarkic Agricultural Households in Rwanda
In situations of imperfect markets and high ratios of ownconsumption which characterise agricultural households in develo** countries, the levels of their agricultural outputs may affect their health status....
