22 Result(s)
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Article
Open AccessSafety of Empagliflozin: An Individual Participant-Level Data Meta-Analysis from Four Large Trials
Empagliflozin is a sodium-glucose co-transporter-2 inhibitor used to treat type 2 diabetes (T2D) to improve glycemic control, reduce risk of cardiovascular death in patients with T2D, and treat patients with s...
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Article
Open AccessGuardians For Health: A Practical Approach to Improving Quality of Life and Longevity in People with Type 2 Diabetes
Type 2 diabetes is one of the fastest-growing health emergencies of the twenty-first century, in part due to its association with cardiovascular and renal disease. Successful implementation of evidence-based g...
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Article
Update zur diastolisch bedingten Herzinsuffizienz
Die neuen Leitlinien der European Society of Cardiology (ESC) zur Herzinsuffizienz von 2021 nehmen eine subtile, klinisch aber relevante Neubewertung der Kategorisierung der Herzinsuffizienz anhand der linksve...
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Article
Open AccessHerzinsuffizienzprotektion bei Patienten mit Diabetes mellitus Typ 2 durch SGLT2-Inhibitoren – Evidenzlage und mögliche Mechanismen
Hemmstoffe des renalen Natrium-Glukose-Kotransporters 2 („sodium glucose-linked transporter 2“; SGLT2i) scheinen außer der antidiabetischen auch eine kardioprotektive Wirkung zu besitzen; deren Mechanismus ist...
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Article
SGLT2 inhibitors: the future for treatment of type 2 diabetes mellitus and other chronic diseases
Individuals with diabetes mellitus exhibit an increased propensity to develop cardiovascular disorders such as coronary artery disease, stroke and heart failure. Over recent decades, numerous cardiovascular ou...
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Article
Empagliflozin in women with type 2 diabetes and cardiovascular disease – an analysis of EMPA-REG OUTCOME®
The global epidemic of type 2 diabetes affects women and men equally; however, the relative impact on the cardiovascular (CV) system appears greater for women than men when compared with peers without diabetes...
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Article
Open AccessPostmarketing experience with Neutrolin® (taurolidine, heparin, calcium citrate) catheter lock solution in hemodialysis patients
Catheter-related bloodstream infections (CRBSI) are major complications for patients with life-threatening conditions requiring chronic vascular catheterization. The wide range of etiologic microbes and the on...
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Article
Chronic kidney disease
Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural abnormalities or impaired excretory renal function suggestive of a loss of functional nephrons. The majority of patients wi...
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Article
Open AccessPatient’s and physician’s awareness of kidney disease in coronary heart disease patients – a cross-sectional analysis of the German subset of the EUROASPIRE IV survey
Chronic kidney disease (CKD) is a common comorbid condition in coronary heart disease (CHD). CKD predisposes the patient to acute kidney injury (AKI) during hospitalization. Data on awareness of kidney dysfunc...
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Article
Open AccessInternational Network of Chronic Kidney Disease cohort studies (iNET-CKD): a global network of chronic kidney disease cohorts
Chronic kidney disease (CKD) is a global health burden, yet it is still underrepresented within public health agendas in many countries. Studies focusing on the natural history of CKD are challenging to design...
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Article
Open AccessGlycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease – cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort
Diabetes mellitus (DM) is the leading cause of end-stage renal disease. Little is known about practice patterns of anti-diabetic therapy in the presence of chronic kidney disease (CKD) and correlates with glyc...
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Living Reference Work Entry In depth
Chronische Niereninsuffizienz: Epidemiologie und Pathophysiologie
Eine chronische Niereninsuffizienz ist definiert als Nierenschaden oder eine eingeschränkte geschätzte glomeruläre Filtrationsrate <60 ml/min/1,73 m2 für einen Zeitraum von mindestens drei Monaten. Der Schweregra...
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Article
Open AccessKidney function as an underestimated factor for reduced health related quality of life in patients with Fabry disease
Impairments of health related quality of life (HRQoL) are frequently observed in Fabry disease (FD) and are known to be related to neuropathic pain and cardiovascular events. This study aimed to explore the ro...
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Article
New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk
After the publication of the new guidelines of the European Society of Cardiology and the European Atherosclerosis Society for the prevention and treatment of dyslipidemias (Eur Heart J 32:1769–1818, 2011; Eur...
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Article
Open AccessPotential role of vitamin D deficiency on Fabry cardiomyopathy
Patients with Fabry disease frequently develop left ventricular (LV) hypertrophy and renal fibrosis. Due to heat intolerance and an inability to sweat, patients tend to avoid exposure to sunlight. We hypothesi...
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Living Reference Work Entry In depth
Chronische Niereninsuffizienz: Kardiovaskuläre Probleme
Etwa 50 % der Ursachen für die stark erhöhte Mortalität von Dialysepatienten sind kardiale und vaskuläre Ereignisse. Eine verminderte glomeruläre Filtrationsrate (GFR) stellt einen unabhängigen Risikofaktor fü...
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Article
Cross-sectional baseline analysis of electrocardiography in a large cohort of patients with untreated Fabry disease
Morphology and function of Fabry cardiomyopathy has been previously studied by echocardiography and cardiac magnetic resonance (CMR). However, the value of electrocardiography (ECG) in relation to these two te...
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Article
Open AccessPredicting erythropoietin resistance in hemodialysis patients with type 2 diabetes
Resistance to ESAs (erythropoietin stimulating agents) is highly prevalent in hemodialysis patients with diabetes and associated with an increased mortality. The aim of this study was to identify predictors fo...
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Article
Frauen mit Morbus Fabry – eine interdisziplinäre diagnostische und therapeutische Herausforderung
Der Morbus Fabry ist eine seltene genetische Speichererkrankung, die zu einer progressiven Akkumulation von Globotriaosylceramiden in den Lysosomen verschiedenster Körperzellen führt. Da die Erkrankung X-chrom...
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Chapter
Membranes for Dialysis and Hemofiltration
Materials for dialyzers and hemofilters are either based on cellulose or modified cellulosic membranes or made from synthetic polymers such as polysulfone, polyethersulfone, polyamide, polyacrylonitrile, or po...
