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Article
Lack of noncanonical RAS mutations in cytogenetically normal acute myeloid leukemia
Transforming mutations in RAS genes are commonly found in human malignancies, including myeloid leukemias. To investigate the incidence, spectrum, and distribution of activating K- and N-RAS mutations in cytogene...
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Article
Molecularly targeted therapies in myelodysplastic syndromes and acute myeloid leukemias
Although there has been significant progress in acute myeloid leukemia (AML) treatment in younger adults during the last decade, standard induction therapy still fails to induce remission in up to 40% of AML p...