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Bile acids for diabetic cardiomyopathy
Diabetes can cause heart failure by a toxic accumulation of lipids in cardiac myocytes, which impairs their function. This work shows that stimulation of the bile acid receptor TGR5 limits fatty acid uptake in...
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Article
Mitochondriale Transhydrogenase: Yin und Yang der antioxidativen Kapazität
Mitochondria are the main source for ATP, but also reactive oxygen species (ROS). While NADH is required for ATP production, NADPH regenerates anti-oxidative capacity to prevent excessive ROS emission. The mit...