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    Article

    Mitochondriale Transhydrogenase: Yin und Yang der antioxidativen Kapazität

    Mitochondria are the main source for ATP, but also reactive oxygen species (ROS). While NADH is required for ATP production, NADPH regenerates anti-oxidative capacity to prevent excessive ROS emission. The mit...

    Albrecht Von Hardenberg, Alexander Nickel, Christoph Maack in BIOspektrum (2017)

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    Mitochondrial Therapies in Heart Failure

    The current therapy for patients with stable systolic heart failure is largely limited to treatments that interfere with neurohormonal activation. Critical pathophysiological hallmarks of heart failure are an ...

    Albrecht von Hardenberg, Christoph Maack in Heart Failure (2017)