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Article
Open AccessInhibin B and anti-Müllerian hormone as markers of gonadal function after hematopoietic cell transplantation during childhood
It is difficult to predict the reproductive capacity of children given hematopoietic cell transplantation (HCT) before pubertal age because the plasma concentrations of follicle-stimulating hormone (FSH) and l...
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Article
Open AccessDiagnosis of growth hormone (GH) deficiency: comparison of pituitary stalk interruption syndrome and transient GH deficiency
Most patients with childhood non-organic growth hormone (GH) deficiency (GHD) produce a normal GH peak as young adults. Our objectives were to better define this transient GHD and evaluate the factors influenc...
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Article
Open AccessChildhood craniopharyngioma: greater hypothalamic involvement before surgery is associated with higher homeostasis model insulin resistance index
Obesity seems to be linked to the hypothalamic involvement in craniopharyngioma. We evaluated the pre-surgery relationship between the degree of this involvement on magnetic resonance imaging and insulin resis...
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Article
Open AccessSelecting short-statured children needing growth hormone testing: Derivation and validation of a clinical decision rule
Numerous short-statured children are evaluated for growth hormone (GH) deficiency (GHD). In most patients, GH provocative tests are normal and are thus in retrospect unnecessary.
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Article
Open AccessFactors influencing the growth hormone peak and plasma insulin-like growth factor I in young adults with pituitary stalk interruption syndrome
The diagnostic criteria for growth hormone (GH) deficiency (GHD) in adolescents and young adults are not yet clearly established.
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Article
Open AccessIdiopathic central precocious puberty in girls: presentation factors
It is sometimes difficult to distinguish between premature thelarche and precocious puberty in girls who develop breasts before the age of 8 years. We evaluated the frequencies of the signs associated with bre...
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Growth and Puberty in Hydrocephalus
Non-tumor-related hydrocephalus may cause short adult height [21, 26], weight gain [11] and/or disorders of puberty [4a, 7, 10, 12]. Although these conditions are believed to be caused by increased pressure on...
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Article
Premature pubarche as an indicator of how body weight influences the onset of adrenarche
Premature pubarche (PP) is defined as the development of pubic and/or axillary hair before the age of 8 years in girls and 9 years in boys. The objective was to obtain a clearer picture of the physiology of ad...
