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    A limited sampling strategy to estimate individual pharmacokinetic parameters of methotrexate in children with acute lymphoblastic leukemia

    The objectives of this study were to characterize the population pharmacokinetics of MTX in patients with acute lymphoblastic leukemia (ALL) with ages ranging from 2 to 16 years and to propose a limited sampli...

    Christine Piard, Françoise Bressolle, May Fakhoury… in Cancer Chemotherapy and Pharmacology (2007)