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Article
Open AccessIntra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study
Chronic low back pain due to disc degeneration represents a major social and economic burden worldwide. The current standard of care is limited to symptomatic relief and no current approved therapy promotes di...
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Article
Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration
The regenerative capacity of skeletal muscle declines with age. Previous studies suggest that this process can be reversed by exposure to young circulation; however, systemic age-specific factors responsible f...
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Article
Open AccessComparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis
A reciprocal relationship between bone and fat development in osteoporosis is clinically well established. Some of the key molecular regulators involved in this tissue replacement process have been identified....
