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Article
Open AccessCheckpoint inhibition through small molecule-induced internalization of programmed death-ligand 1
Programmed death-ligand 1 is a glycoprotein expressed on antigen presenting cells, hepatocytes, and tumors which upon interaction with programmed death-1, results in inhibition of antigen-specific T cell respo...
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Article
Open AccessPublisher Correction: Circulating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessCirculating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients
Chronic hepatitis B (CHB) infection functional cure is defined as sustained loss of HBsAg and several therapeutic strategies are in clinical development designed to pharmacologically reduce serum HBsAg, break ...
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Article
NLRX1 is a regulator of mitochondrial antiviral immunity
Cytoplasmic RIG-like helicases are sensors of viral RNA, and signal through the mitochondrial adaptor protein MAVS to activate IRF3 and induce type 1 interferon production. This paper shows that a member of th...