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  1. Article

    Open Access

    Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1

    Programmed death-ligand 1 is a glycoprotein expressed on antigen presenting cells, hepatocytes, and tumors which upon interaction with programmed death-1, results in inhibition of antigen-specific T cell respo...

    Jang-June Park, Emily P. Thi, Victor H. Carpio, Yingzhi Bi in Nature Communications (2021)

  2. Article

    Open Access

    Publisher Correction: Circulating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    ** Hyang Kim, Alip Ghosh, Natarajan Ayithan, Sara Romani in Scientific Reports (2020)

  3. Article

    Open Access

    Circulating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients

    Chronic hepatitis B (CHB) infection functional cure is defined as sustained loss of HBsAg and several therapeutic strategies are in clinical development designed to pharmacologically reduce serum HBsAg, break ...

    ** Hyang Kim, Alip Ghosh, Natarajan Ayithan, Sara Romani in Scientific Reports (2020)

  4. No Access

    Article

    NLRX1 is a regulator of mitochondrial antiviral immunity

    Cytoplasmic RIG-like helicases are sensors of viral RNA, and signal through the mitochondrial adaptor protein MAVS to activate IRF3 and induce type 1 interferon production. This paper shows that a member of th...

    Chris B. Moore, Daniel T. Bergstralh, Joseph A. Duncan, Yu Lei in Nature (2008)