2 Result(s)
within
Chor-Sang Chim
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessA proof-of-concept study for the pathogenetic role of enhancer hypomethylation of MYBPHL in multiple myeloma
Enhancer DNA methylation and expression of MYBPHL was studied in multiple myeloma (MM). By bisulfite genomic sequencing, among the three CpGs inside the MYBPHL enhancer, CpG1 was significantly hypomethylated in M...
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Article
Open AccessFrequent functional activation of RAS signalling not explained by RAS/RAF mutations in relapsed/refractory multiple myeloma
RAS mutations are frequent in relapsed/refractory multiple myeloma (RRMM) but functional study in primary samples is scanty. Herein, in primary myeloma plasma cells of 17 suspected RRMM, functional activation of ...
