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Article
Open AccessProgress of tissue adhesives based on proteins and synthetic polymers
In recent years, polymer-based tissue adhesives (TAs) have been developed as an alternative to sutures to close and seal incisions or wounds owing to their ease of use, rapid application time, low cost, and mi...
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Article
Enhancement of Immune Responses Elicited by Nanovaccines through a Cross-Presentation Pathway
Numerous studies have aimed to develop novel advanced vaccines, in part because traditional vaccines have been unsuccessful in preventing rapidly emerging and reemerging viral and bacterial infections. There i...
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Article
Bone Morphogenic Protein-2-Conjugated Three-Dimensional-Printed Poly (L-Lactic Acid) (PLLA) Scaffold is likely Promising as an Effective Bone Substitute
Bone morphogenic protein-2 (BMP-2)-conjugated three-dimensional (3-D)-printed poly (L-lactic acid)(PLLA) scaffold is likely promising as an effective bone substitute for enhancing bone regeneration of massive ...
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Article
Progress of Polysaccharide-Contained Polyurethanes for Biomedical Applications
Polyurethane (PU) has been widely examined and used for biomedical applications, such as catheters, blood oxygenators, stents, cardiac valves, drug delivery carriers, dialysis devices, wound dressings, adhesiv...
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Article
Open AccessIn vitro photodynamic therapy of methylene blue-loaded acetyl resistant starch nanoparticles
Combination therapies comprising multiple methods, such as photodynamic therapy have been applied to be complements chemotherapy as they increase the therapeutic efficiency by enabling the intelligent drug del...
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Article
Mucosal Vaccine Delivery Using Mucoadhesive Polymer Particulate Systems
Vaccination has been recently attracted as one of the most successful medical treatments of the prevalence of many infectious diseases. Mucosal vaccination has been interested in many researchers because mucos...
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Chapter
Recent Progress in Biomedical Applications of Chitosan Derivatives as Gene Carrier
Appropriate gene carriers are vital components of gene therapy for treating numerous intractable diseases. Compared with viral carriers, non-viral carriers exhibit lower immunogenicity and higher biosafety, wh...
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Article
Induced Circular Dichroism of Methylene Blue in Self-Assembled Pullulan Nanoparticles
This study reports self-assembled pullulan nanoparticles (PUNPs) obtained by the diafiltration method after dissolving phthalic pullulan in dimethylformamide, which was prepared by esterification between the p...
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Article
Applications of Organoids for Tissue Engineering and Regenerative Medicine
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Article
Additive anti-inflammation by a combination of conjugated linoleic acid and α-lipoic acid through molecular interaction between both compounds
Alpha lipoic acid (LA) and conjugated linoleic acid (CLA) have been well-documented on a variety of functional effects in health foods. The main purpose of this study was focused on the additive anti-inflammat...
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Article
Enhanced Efficacy of Immunization with a Foot-and-Mouth Disease Multi-Epitope Subunit Vaccine Using Mannan-Decorated Inulin Microparticles
Despite the many advantages of recombinant subunit vaccines, they have critical weaknesses that include a low efficacy for promoting cellular and humoral immune responses against antigens because of their poor...
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Article
Updates in molecular imaging techniques
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Updates in Cartilage Tissue Regeneration
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Article
Efficient Mucosal Immunization by Mucoadhesive and pH-Sensitive Polymeric Vaccine Delivery System
Mucosal surfaces as the largest immune organ of human body cover 400 m2 of the body including the gastrointestinal, urogenital, and respiratory tracts. The local mucosal immunity is an important first line of def...
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Article
Injectable Hydrogels for Regenerative Medicine
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Injectable Biomaterials in Plastic and Reconstructive Surgery: A Review of the Current Status
Injectable biomaterials have attracted increasing attention for volume restoration and tissue regeneration. The main aim of this review is to discuss the current status of the injectable biomaterials for corre...
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Article
Open AccessA new way of producing pediocin in Pediococcus acidilactici through intracellular stimulation by internalized inulin nanoparticles
One of the most challenging aspects of probiotics as a replacement for antibiotics is to enhance their antimicrobial activity against pathogens. Given that prebiotics stimulate the growth and/or activity of pr...
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Article
Oral Immunization of FMDV Vaccine Using pH-Sensitive and Mucoadhesive Thiolated Cellulose Acetate Phthalate Microparticles
Several barriers such as gastric pH, enzymatic degradation and rapid transit should be overcome to orally deliver antigens for taking up by epithelial microfold cells in Peyer’s patches of small intestine. To ...
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Chapter
Degradable Polyethylenimine-Based Gene Carriers for Cancer Therapy
Gene therapy using recombinant DNA or gene silencing using siRNA have become a prominent area of research in cancer therapy. However, their use in clinical applications is limited due to overall safety concern...
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Article
Improved antimicrobial activity of Pediococcus acidilactici against Salmonella Gallinarum by UV mutagenesis and genome shuffling
Pediococcus acidilactici is a widely used probiotic, and Salmonella enterica serovar Gallinarum (SG) is a significant pathogen in the poultry industry. In this study, we improved the anti...
