4 Result(s)
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Article
Open AccessThe prognostic significance of immune microenvironment in breast ductal carcinoma in situ
The role of different subtypes of tumour infiltrating lymphocytes (TILs) in breast ductal carcinoma in situ (DCIS) is still poorly defined. This study aimed to assess the prognostic significance of B and T lym...
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Article
Open AccessRetinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer
Retinoid X Receptor Gamma (RXRG) is a member of the nuclear receptor superfamily and plays a role in tumour suppression. This study aims to explore the prognostic significance of RXRG in breast cancer.
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Article
Open AccessA key genomic subtype associated with lymphovascular invasion in invasive breast cancer
Lymphovascular invasion (LVI) is associated with the development of metastasis in invasive breast cancer (BC). However, the complex molecular mechanisms of LVI, which overlap with other oncogenic pathways, rem...
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Article
Open AccessMediator complex (MED) 7: a biomarker associated with good prognosis in invasive breast cancer, especially ER+ luminal subtypes
Mediator complex (MED) proteins have a key role in transcriptional regulation, some interacting with the oestrogen receptor (ER). Interrogation of the METABRIC cohort suggested that MED7 may regulate lymphovas...
