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Article
Open AccessEmpirical treatment against cytomegalovirus and tuberculosis in HIV-infected infants with severe pneumonia: study protocol for a multicenter, open-label randomized controlled clinical trial
Pneumonia is the primary cause of death among HIV-infected children in Africa, with mortality rates as high as 35–40% in infants hospitalized with severe pneumonia. Bacterial pathogens and Pneumocystis jirovecii ...
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Article
Open AccessImpact of systematic early tuberculosis detection using Xpert MTB/RIF Ultra in children with severe pneumonia in high tuberculosis burden countries (TB-Speed pneumonia): a stepped wedge cluster randomized trial
In high tuberculosis (TB) burden settings, there is growing evidence that TB is common in children with pneumonia, the leading cause of death in children under 5 years worldwide. The current WHO standard of ca...
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Article
Open AccessShorter treatment for minimal tuberculosis (TB) in children (SHINE): a study protocol for a randomised controlled trial
Tuberculosis (TB) in children is frequently paucibacillary and non-severe forms of pulmonary TB are common. Evidence for tuberculosis treatment in children is largely extrapolated from adult studies. Trials in...
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Article
Open AccessTuberculosis caseload in children with severe acute malnutrition related with high hospital based mortality in Lusaka, Zambia
Tuberculosis and severe acute malnutrition (SAM) in children pose a major treatment and care challenge in high HIV burden countries in Africa. We investigated the prevalence of Tuberculosis notifications among...
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Article
Open AccessErratum to: Knowledge and perceptions of asthma in Zambia: a cross-sectional survey
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Article
Open AccessKnowledge and perceptions of asthma in Zambia: a cross-sectional survey
Zambia is currently experiencing an epidemiological transition, from communicable to non-communicable diseases. The annual rate of physician-diagnosed asthma is estimated at 3 %. However, the general public’s ...